Table 2.

Changes in estrogen-sensitive hemostatic biomarkers (nAPCsr, nTM sr, and SHBG) among those who stopped using CHCs

Women who stopped using CHCs (n = 66)
nAPCsrnTMsrSHBG (nmol/L)
nMean (SD)Relative decreasenMean (SD)Relative decreasenMean (SD)Relative decrease
Baseline 64 4.11 (2.06) Ref 63 2.53 (1.04) Ref 66 167 (103) Ref 
1 wk 62 2.34 (1.50) 62.1% 63 1.69 (0.88) 59.7% 66 123 (76.0) 39.8% 
2 wk 56 1.67 (0.98) 85.8% 60 1.38 (0.69) 81.3% 66 81.9 (41.8) 76.2% 
4 wk 50 1.64 (1.17) 86.7% 55 1.32 (0.66) 85.5% 64 69.0 (35.3) 87.8% 
6 wk 46 1.37 (0.84) 96.4% 54 1.24 (0.65) 91.3% 61 59.5 (31.7) 96.4% 
12 wk 45 1.27 (0.82) 100% 59 1.11 (0.58) 100% 66 55.4 (26.7) 100% 
Women who stopped using CHCs (n = 66)
nAPCsrnTMsrSHBG (nmol/L)
nMean (SD)Relative decreasenMean (SD)Relative decreasenMean (SD)Relative decrease
Baseline 64 4.11 (2.06) Ref 63 2.53 (1.04) Ref 66 167 (103) Ref 
1 wk 62 2.34 (1.50) 62.1% 63 1.69 (0.88) 59.7% 66 123 (76.0) 39.8% 
2 wk 56 1.67 (0.98) 85.8% 60 1.38 (0.69) 81.3% 66 81.9 (41.8) 76.2% 
4 wk 50 1.64 (1.17) 86.7% 55 1.32 (0.66) 85.5% 64 69.0 (35.3) 87.8% 
6 wk 46 1.37 (0.84) 96.4% 54 1.24 (0.65) 91.3% 61 59.5 (31.7) 96.4% 
12 wk 45 1.27 (0.82) 100% 59 1.11 (0.58) 100% 66 55.4 (26.7) 100% 

The relative decrease was calculated as the proportion of the absolute difference between baseline and 12 weeks that was obtained at each study time point.

Ref, reference group.

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