Cell types and antigen expression patterns used to detect them
Cell type . | Expression pattern . |
---|---|
HSPCs | CD34+/negative for all other markers |
Myeloblasts | CD34+/CD117+ |
Promyelocytes | CD117+/CD15+ |
Proerythroblasts | CD117+/CD71+ |
Erythroid normoblasts | CD71+/negative for all other markers |
MMCs | CD15+/negative for all other markers |
Megakaryocytes | CD61+/negative for all other markers |
Likely B-cell precursors | CD38+ (moderate) /negative for all other markers, with small cell size and high N:C ratio |
Likely plasma cells | CD38+ (strong) /negative for all other markers, with larger cell size and high N:C ratio |
Mast cells | CD117+ (strong) /negative for all other markers |
Nonhematopoietic elements (NHEs) | Negative for all markers |
Cell type . | Expression pattern . |
---|---|
HSPCs | CD34+/negative for all other markers |
Myeloblasts | CD34+/CD117+ |
Promyelocytes | CD117+/CD15+ |
Proerythroblasts | CD117+/CD71+ |
Erythroid normoblasts | CD71+/negative for all other markers |
MMCs | CD15+/negative for all other markers |
Megakaryocytes | CD61+/negative for all other markers |
Likely B-cell precursors | CD38+ (moderate) /negative for all other markers, with small cell size and high N:C ratio |
Likely plasma cells | CD38+ (strong) /negative for all other markers, with larger cell size and high N:C ratio |
Mast cells | CD117+ (strong) /negative for all other markers |
Nonhematopoietic elements (NHEs) | Negative for all markers |