Table 3.

Linear regression model of associations between CTCAE grade 2 to 4 chronic conditions and neurocognitive outcomes of survivors, adjusted for sex

Outcome CardiacVascularEndocrineNeurologicPulmonary
EstPEstPEstPEstPEstP
Sustained attention −0.126 .55 −0.333 .095 −0.061 .77 −0.750 .0008 −0.482 .012 
Visuomotor speed 0.005 .97 −0.294 .033 −0.149 .30 −0.676 <.0001 −0.191 .15 
Visual speed −0.052 .72 −0.195 .17 −0.368 .012 −0.351 .029 −0.244 .074 
Motor speed 0.200 .20 −0.340 .025 −0.142 .37 −0.697 <.0001 −0.102 .49 
Learning 0.162 .31 0.057 .71 −0.219 .16 −0.591 .0006 −0.203 .17 
Short-term recall 0.259 .096 0.027 .86 −0.123 .43 −0.199 .25 −0.056 .70 
Long-term recall 0.361 .038 −0.044 .79 −0.240 .17 −0.190 .32 −0.139 .39 
Cognitive flexibility 0.111 .56 −0.090 .62 −0.286 .13 −0.669 .001 −0.207 .24 
Outcome CardiacVascularEndocrineNeurologicPulmonary
EstPEstPEstPEstPEstP
Sustained attention −0.126 .55 −0.333 .095 −0.061 .77 −0.750 .0008 −0.482 .012 
Visuomotor speed 0.005 .97 −0.294 .033 −0.149 .30 −0.676 <.0001 −0.191 .15 
Visual speed −0.052 .72 −0.195 .17 −0.368 .012 −0.351 .029 −0.244 .074 
Motor speed 0.200 .20 −0.340 .025 −0.142 .37 −0.697 <.0001 −0.102 .49 
Learning 0.162 .31 0.057 .71 −0.219 .16 −0.591 .0006 −0.203 .17 
Short-term recall 0.259 .096 0.027 .86 −0.123 .43 −0.199 .25 −0.056 .70 
Long-term recall 0.361 .038 −0.044 .79 −0.240 .17 −0.190 .32 −0.139 .39 
Cognitive flexibility 0.111 .56 −0.090 .62 −0.286 .13 −0.669 .001 −0.207 .24 

Each row denotes 1 independent model that includes all the chronic condition as explanatory variables.

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