Table 1.

Patient clinical and demographic characteristics total number

Median age (range) 60 (46-90) 
Male, n (%) 28 (78) 
ECOG, n (%)  
0/1 34 (94) 
2 (6) 
Stage at initial diagnosis, n (%)  
I/II 5 (14) 
III/IV 28 (78) 
Unknown 3 (8) 
MIPI  
Low 18 (50) 
Intermediate 7 (19) 
High 11 (31) 
Extranodal disease at initial diagnosis, n (%) 9 (25) 
Induction therapy, n (%)  
BR 17 (47) 
R-HyperCVAD 9 (25) 
Nordic Regimen (maxi-RCHOP/HiDAC) 7 (19) 
R-CHOP/DHAP 2 (6) 
R-CHOP 1 (3) 
auto-SCT consolidation before enrollment, n (%) 18 (50) 
Best response to induction therapy before enrollment, n (%)  
CR 34 (94) 
PR 2 (6) 
MRD status after induction therapy (n = 22)  
MRD (−)  17 (77) 
MRD indeterminate (defined as <1 × 106 cells assayed) 4 (18) 
MRD (+)  1 (5) 
Median age (range) 60 (46-90) 
Male, n (%) 28 (78) 
ECOG, n (%)  
0/1 34 (94) 
2 (6) 
Stage at initial diagnosis, n (%)  
I/II 5 (14) 
III/IV 28 (78) 
Unknown 3 (8) 
MIPI  
Low 18 (50) 
Intermediate 7 (19) 
High 11 (31) 
Extranodal disease at initial diagnosis, n (%) 9 (25) 
Induction therapy, n (%)  
BR 17 (47) 
R-HyperCVAD 9 (25) 
Nordic Regimen (maxi-RCHOP/HiDAC) 7 (19) 
R-CHOP/DHAP 2 (6) 
R-CHOP 1 (3) 
auto-SCT consolidation before enrollment, n (%) 18 (50) 
Best response to induction therapy before enrollment, n (%)  
CR 34 (94) 
PR 2 (6) 
MRD status after induction therapy (n = 22)  
MRD (−)  17 (77) 
MRD indeterminate (defined as <1 × 106 cells assayed) 4 (18) 
MRD (+)  1 (5) 

BR, bendamustine-rituximab; ECOG, Eastern Cooperative Oncology Group; MIPI, Mantle Cell Lymphoma International Prognostic Index.

1 with PR radiographically by CT.

Induced with BR before enrollment; radiographic CR by CT.

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