Patient clinical and demographic characteristics total number
Median age (range) | 60 (46-90) |
Male, n (%) | 28 (78) |
ECOG, n (%) | |
0/1 | 34 (94) |
2 | 2 (6) |
Stage at initial diagnosis, n (%) | |
I/II | 5 (14) |
III/IV | 28 (78) |
Unknown | 3 (8) |
MIPI | |
Low | 18 (50) |
Intermediate | 7 (19) |
High | 11 (31) |
Extranodal disease at initial diagnosis, n (%) | 9 (25) |
Induction therapy, n (%) | |
BR | 17 (47) |
R-HyperCVAD | 9 (25) |
Nordic Regimen (maxi-RCHOP/HiDAC) | 7 (19) |
R-CHOP/DHAP | 2 (6) |
R-CHOP | 1 (3) |
auto-SCT consolidation before enrollment, n (%) | 18 (50) |
Best response to induction therapy before enrollment, n (%) | |
CR | 34 (94) |
PR | 2 (6) |
MRD status after induction therapy (n = 22) | |
MRD (−)∗ | 17 (77) |
MRD indeterminate (defined as <1 × 106 cells assayed) | 4 (18) |
MRD (+)† | 1 (5) |
Median age (range) | 60 (46-90) |
Male, n (%) | 28 (78) |
ECOG, n (%) | |
0/1 | 34 (94) |
2 | 2 (6) |
Stage at initial diagnosis, n (%) | |
I/II | 5 (14) |
III/IV | 28 (78) |
Unknown | 3 (8) |
MIPI | |
Low | 18 (50) |
Intermediate | 7 (19) |
High | 11 (31) |
Extranodal disease at initial diagnosis, n (%) | 9 (25) |
Induction therapy, n (%) | |
BR | 17 (47) |
R-HyperCVAD | 9 (25) |
Nordic Regimen (maxi-RCHOP/HiDAC) | 7 (19) |
R-CHOP/DHAP | 2 (6) |
R-CHOP | 1 (3) |
auto-SCT consolidation before enrollment, n (%) | 18 (50) |
Best response to induction therapy before enrollment, n (%) | |
CR | 34 (94) |
PR | 2 (6) |
MRD status after induction therapy (n = 22) | |
MRD (−)∗ | 17 (77) |
MRD indeterminate (defined as <1 × 106 cells assayed) | 4 (18) |
MRD (+)† | 1 (5) |