Comparison of selected major societal guideline recommendations for correction of hemostatic parameters prior to high bleeding risk procedures
| . | BSIR 20228 . | EASL 20225 . | ISTH 20216 . | AGA 20217 . | AASLD 20204 . | SIR 201951 . |
|---|---|---|---|---|---|---|
| PT/INR | Do not correct | Do not correct | Do not evaluate | Do not correct | Do not correct | INR >2.5* |
| Platelets | Consider if <50 × 109/L | Case by case for <50 × 109/L | Do not correct† | Do not correct | Do not correct | >30 × 109/L |
| Fibrinogen | Consider if <1.2 g/l | Correction discouraged | Do not evaluate | No recommendation | Do not correct | >1 g/L |
| . | BSIR 20228 . | EASL 20225 . | ISTH 20216 . | AGA 20217 . | AASLD 20204 . | SIR 201951 . |
|---|---|---|---|---|---|---|
| PT/INR | Do not correct | Do not correct | Do not evaluate | Do not correct | Do not correct | INR >2.5* |
| Platelets | Consider if <50 × 109/L | Case by case for <50 × 109/L | Do not correct† | Do not correct | Do not correct | >30 × 109/L |
| Fibrinogen | Consider if <1.2 g/l | Correction discouraged | Do not evaluate | No recommendation | Do not correct | >1 g/L |
AASLD, American Association for the Study of Liver Disease; AGA, American Gastroenterology Association; EASL, European Association for the Study of Liver Diseases; BSIR, British Society of Interventional Radiology; INR, international normalized ratio; ISTH, International Society of Thrombosis and Haemostasis; PT, prothrombin time; SIR, Society of Interventional Radiology.
Give vitamin K if INR >2.5; do not use fresh frozen plasma or prothrombin complex concentrate.
Consider correction prior to planned elective very-high-risk procedures.