Table 1.

Procedural bleeding risk classification of commonly performed procedures in patients with advanced chronic liver disease from the International Society of Thrombosis and Haemostasis Scientific Subcommittee

Low bleeding riskHigh bleeding risk*
Endoscopic Diagnostic procedures
Endoscopic variceal ligation
Transesophageal echocardiogram 
Bronchoscopy with biopsy
Colonoscopy with polypectomy
Endoscopic retrograde cholangiopancreatography with sphincterotomy 
Percutaneous Paracentesis
Thoracocentesis 
Percutaneous liver biopsy
Tunneled ascitic/pleural drain placement
Cranial/spinal surgery# 
Vascular Peripheral/central venous catheterization
Transjugular liver biopsy 
Transjugular intrahepatic portosystemic shunt
Transcatheter arterial chemoembolization 
Other Dental procedures including extractions
Skin biopsy 
Intraocular procedures# 
Low bleeding riskHigh bleeding risk*
Endoscopic Diagnostic procedures
Endoscopic variceal ligation
Transesophageal echocardiogram 
Bronchoscopy with biopsy
Colonoscopy with polypectomy
Endoscopic retrograde cholangiopancreatography with sphincterotomy 
Percutaneous Paracentesis
Thoracocentesis 
Percutaneous liver biopsy
Tunneled ascitic/pleural drain placement
Cranial/spinal surgery# 
Vascular Peripheral/central venous catheterization
Transjugular liver biopsy 
Transjugular intrahepatic portosystemic shunt
Transcatheter arterial chemoembolization 
Other Dental procedures including extractions
Skin biopsy 
Intraocular procedures# 
*

Classification based on major bleeding >1.5% or on minor bleeding associated with high risk of significant organ damage/death.

#

Very high-risk procedures.

Reproduced with permission from Elsevier Inc.

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