Price summary of MAPK inhibitors with regimens/doses
| Drug . | Regimen-dose/cost: USD/month . | |
|---|---|---|
| Adults . | Children (weight = 20 kg) . | |
| Vemurafenib | 480-960 mg bid/$6500-$12 500 | 20 mg/kg/d div bid/$2600 (200 mg bid) |
| Dabrafenib | 75-150 mg bid/$8500-$16 500 | 5.25 mg/kg/d div bid/$5500 (50 mg bid) |
| Trametinib | 1-2 mg qd/$8400-$16 800 | 0.025 mg/k/d qd/$4200 (0.5 mg/d) |
| Cobimetinib | 20-60 mg qd × 21 of 28-day cycle/$10 000-$30 000 | 1 mg/kg/d $10 000-$13 000 (20-25 mg/d) |
| Drug . | Regimen-dose/cost: USD/month . | |
|---|---|---|
| Adults . | Children (weight = 20 kg) . | |
| Vemurafenib | 480-960 mg bid/$6500-$12 500 | 20 mg/kg/d div bid/$2600 (200 mg bid) |
| Dabrafenib | 75-150 mg bid/$8500-$16 500 | 5.25 mg/kg/d div bid/$5500 (50 mg bid) |
| Trametinib | 1-2 mg qd/$8400-$16 800 | 0.025 mg/k/d qd/$4200 (0.5 mg/d) |
| Cobimetinib | 20-60 mg qd × 21 of 28-day cycle/$10 000-$30 000 | 1 mg/kg/d $10 000-$13 000 (20-25 mg/d) |