Table 3.

Currently reported studies utilizing HMA-VEN for remission induction prior to allogeneic SCT

StudyTypeParticipating sitesNumber of patients12-month NRM (%)12-month CIR12-month RFS (%)12-month OS (%)Relapse (%)/median LFS (month)OS (months)
Pasvolsky et al35  Retrospective Multicenter 24 19.1  58 63   
Winters et al36  Retrospective Single center 29   66.1 74.5   
Pollyea et al37,38  Retrospective Single center 21 11  80   NR 
Kennedy et al39,40  Retrospective Multicenter 88 17 18  73   
Nizamuddin et al41  Retrospective Single center 36     39/11.2 25.4 
Rautenberg et al42  Retrospective Single center 26   67 81  NR 
StudyTypeParticipating sitesNumber of patients12-month NRM (%)12-month CIR12-month RFS (%)12-month OS (%)Relapse (%)/median LFS (month)OS (months)
Pasvolsky et al35  Retrospective Multicenter 24 19.1  58 63   
Winters et al36  Retrospective Single center 29   66.1 74.5   
Pollyea et al37,38  Retrospective Single center 21 11  80   NR 
Kennedy et al39,40  Retrospective Multicenter 88 17 18  73   
Nizamuddin et al41  Retrospective Single center 36     39/11.2 25.4 
Rautenberg et al42  Retrospective Single center 26   67 81  NR 

CIR, cumulative index of relapse; NR, not reached; NRM, onrelapse mortality; RFS, relapse free survival; LFS, leukemia free survival.

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