Blood parameters in Hbbth3/+ vs Foxo3−/−/Hbbth3/+
Parameters . | WT . | Foxo3−/− . | Hbbth3/+ . | Foxo3−/−/Hbbth3/+ . |
---|---|---|---|---|
RBC (109/L) | 10 400 ± 300 | 9000 ± 100∗ | 6700 ± 700∗ | 7500 ± 600† |
HGB (g/dL) | 15.0 ± 0.3 | 14.8 ± 0.1 | 8.2 ± 0.3∗ | 9.2 ± 0.7† |
HCT (%) | 54.6 ± 1.6 | 52.8 ± 0.9 | 29.3 ± 5.2∗ | 34.5 ± 3.9† |
MCV (fL) | 52.8 ± 1.2 | 58.5 ± 0.8∗ | 41.2 ± 1.4∗ | 45.1 ± 3.0† |
MCH (pg) | 14.6 ± 0.2 | 16.4 ± 0.2 | 12.7 ± 1.6∗ | 12.5 ± 0.4 |
MCHC (g/dL) | 27.4 ± 0.5 | 28.0 ± 0.3 | 30.2 ± 4.1 | 27.2 ± 1.4† |
Retic (%) | 3.6 ± 0.3 | 6.6 ± 0.5∗ | 24.0 ± 5.7∗ | 28.3 ± 7.0 |
n (mice) | 9 | 10 | 7 | 10 |
Parameters . | WT . | Foxo3−/− . | Hbbth3/+ . | Foxo3−/−/Hbbth3/+ . |
---|---|---|---|---|
RBC (109/L) | 10 400 ± 300 | 9000 ± 100∗ | 6700 ± 700∗ | 7500 ± 600† |
HGB (g/dL) | 15.0 ± 0.3 | 14.8 ± 0.1 | 8.2 ± 0.3∗ | 9.2 ± 0.7† |
HCT (%) | 54.6 ± 1.6 | 52.8 ± 0.9 | 29.3 ± 5.2∗ | 34.5 ± 3.9† |
MCV (fL) | 52.8 ± 1.2 | 58.5 ± 0.8∗ | 41.2 ± 1.4∗ | 45.1 ± 3.0† |
MCH (pg) | 14.6 ± 0.2 | 16.4 ± 0.2 | 12.7 ± 1.6∗ | 12.5 ± 0.4 |
MCHC (g/dL) | 27.4 ± 0.5 | 28.0 ± 0.3 | 30.2 ± 4.1 | 27.2 ± 1.4† |
Retic (%) | 3.6 ± 0.3 | 6.6 ± 0.5∗ | 24.0 ± 5.7∗ | 28.3 ± 7.0 |
n (mice) | 9 | 10 | 7 | 10 |