Risky health behaviors and hazard of subsequent all-cause and nonrecurrence–related late mortality
| Variables of interest . | Crude HR (95% CI) . | aHR (95% CI) . | |
|---|---|---|---|
| All-cause mortality . | All-cause mortality . | Nonrecurrence-related mortality . | |
| Ever smoke∗ | |||
| No | Reference | Reference | Reference |
| Yes | 1.5 (1.4-1.8) | 1.2 (1.1-1.5) | 1.3 (1.0-1.8) |
| Smoking status∗ | |||
| Non-smoker | Reference | Reference | Reference |
| Former smoker | 1.6 (1.4-1.8) | 1.2 (1.1-1.5) | 1.3 (1.0-1.8) |
| Current smoker | 1.4 (1.1-1.9) | 1.7 (1.2-2.5) | 1.6 (1.0-2.7) |
| Ever drink alcohol† | |||
| No | Reference | Reference | Reference |
| Yes | 1.3 (1.1-1.5) | 1.1 (0.9-1.3) | 1.1 (0.9-1.4) |
| Heavy drinker† | |||
| No | Reference | Reference | Reference |
| Yes | 0.9 (0.7-1.2) | 1.4 (1.0-1.8) | 1.4 (1.0-2.0) |
| Vigorous physical activity for at least 10 min at a time§ | |||
| Yes | Reference | Reference | Reference |
| No | 1.5 (1.3-1.7) | 1.2 (1.1-1.4) | 1.2 (1.0-1.6) |
| Levels of vigorous exercise (total metabolic equivalent h/wk-1)§ | |||
| ≥ 9 MET h/wk-1 | Reference | Reference | Reference |
| 3 to <9 MET h/wk-1 | 0.6 (0.4-0.8) | 0.7 (0.5-1.0) | 0.7 (0.6-0.1) |
| 0 MET h/wk-1 | 1.4 (1.2-1.7) | 1.3 (1.1-1.7) | 1.3 (1.0-1.7) |
| Variables of interest . | Crude HR (95% CI) . | aHR (95% CI) . | |
|---|---|---|---|
| All-cause mortality . | All-cause mortality . | Nonrecurrence-related mortality . | |
| Ever smoke∗ | |||
| No | Reference | Reference | Reference |
| Yes | 1.5 (1.4-1.8) | 1.2 (1.1-1.5) | 1.3 (1.0-1.8) |
| Smoking status∗ | |||
| Non-smoker | Reference | Reference | Reference |
| Former smoker | 1.6 (1.4-1.8) | 1.2 (1.1-1.5) | 1.3 (1.0-1.8) |
| Current smoker | 1.4 (1.1-1.9) | 1.7 (1.2-2.5) | 1.6 (1.0-2.7) |
| Ever drink alcohol† | |||
| No | Reference | Reference | Reference |
| Yes | 1.3 (1.1-1.5) | 1.1 (0.9-1.3) | 1.1 (0.9-1.4) |
| Heavy drinker† | |||
| No | Reference | Reference | Reference |
| Yes | 0.9 (0.7-1.2) | 1.4 (1.0-1.8) | 1.4 (1.0-2.0) |
| Vigorous physical activity for at least 10 min at a time§ | |||
| Yes | Reference | Reference | Reference |
| No | 1.5 (1.3-1.7) | 1.2 (1.1-1.4) | 1.2 (1.0-1.6) |
| Levels of vigorous exercise (total metabolic equivalent h/wk-1)§ | |||
| ≥ 9 MET h/wk-1 | Reference | Reference | Reference |
| 3 to <9 MET h/wk-1 | 0.6 (0.4-0.8) | 0.7 (0.5-1.0) | 0.7 (0.6-0.1) |
| 0 MET h/wk-1 | 1.4 (1.2-1.7) | 1.3 (1.1-1.7) | 1.3 (1.0-1.7) |
Bolded values indicate statistical significance (CI does not include 1).
Adjusted for sex, race/ethnicity, BMT era, time from BMT to study entry, age at BMT, primary diagnosis, stem cell source, disease status at BMT, BMT type, cGvHD, conditioning intensity, TBI, cyclophosphamide, nitrosoureas, busulfan, fludarabine, household income, educational status, chronic health conditions, mental health, physical activity status, alcohol consumption (ever), and total years of smoking. Survivors with missing smoking status were excluded from this analysis.
Adjusted for sex, race/ethnicity, BMT era, time from BMT to study entry, stem cell source, age at BMT, primary diagnosis, disease status at BMT, BMT type, cGvHD, conditioning intensity, TBI, cyclophosphamide, nitrosoureas, busulfan, fludarabine, household income, chronic health conditions, educational status, mental health, physical activity status, and smoking status (ever). Survivors with missing alcohol consumption status were missing from this analysis.
Adjusted for sex, race/ethnicity, BMT era, time from BMT to study entry, stem cell source, age at BMT, primary diagnosis, disease status at BMT, BMT type, cGvHD, conditioning intensity, TBI, cyclophosphamide, nitrosoureas, busulfan, fludarabine, household income, chronic health condition, educational status, mental health, anxiety from cancer treatment, smoking status (ever), and alcohol consumption (ever). Survivors with missing physical activity status were excluded from this analysis.