Cox regression association statistics
| P . | ICD10 code . | Description . | No. of participants with an event . | log hazard ratio . |
|---|---|---|---|---|
| 5.14 × 10–8 | I26 | Pulmonary embolism | 6 942 | 0.07 |
| 5.50 × 10–6 | I21 | Acute myocardial infarction | 14 198 | 0.04 |
| P . | ICD10 code . | Description . | No. of participants with an event . | log hazard ratio . |
|---|---|---|---|---|
| 5.14 × 10–8 | I26 | Pulmonary embolism | 6 942 | 0.07 |
| 5.50 × 10–6 | I21 | Acute myocardial infarction | 14 198 | 0.04 |
Significant associations (at a family-wise error rate <0.05, equivalent to P < 9.54 × 10–5) between the genetic score of PR and ICD10-coded health outcomes in 384 059 unrelated, British-ancestry participants in UK Biobank. ICD10 subterms (ie, containing a “.”) were collapsed into the parent term. Only collapsed terms assigned to at least 1000 participants were analyzed (524 terms in total).