Summary of descriptive characteristics of included studies evaluating marital status (n = 10) and education level (n = 19)
| Author (year) . | Data source years . | US region . | Patients N . | Outcome/analysis . | Cohorts . | HR (95%-CI) . | Social determinant associated with worse survival . |
|---|---|---|---|---|---|---|---|
| Marital status | |||||||
| Yung et al,19 (2011) | NYSCR 2001–2008 | NY | HL 4752 | OS/multi | Married Unmarried | Ref. 1.49 (1.11-1.99)∗ | Unmarried |
| CCR 2000–2007 | CA | HL 4752 | OS/multi | Married Unmarried | Ref. 1.26 (0.97-1.64) | - | |
| Tao et al,25 (2014) | CCR 2001-2009 | CA | NHL 16 133 | CSS/multi | Married Never married Previously married | Ref. 1.13 (1.07-1.20)∗, 1.13 (1.09-1.18)∗ | Unmarried |
| Huang et al,31 (2021) | SEER 2007-2016 | National | MM 17 981 | CSS/multi | Married Single | Ref. 1.15 (1.06-1.24)∗ | Single |
| OS/multi | Married Single Other | Ref. 1.29 (1.22-1.38)∗, 1.35 (1.26-1.44)∗ | Single, divorced, separated, domestic partner, or widowed | ||||
| Makhani (2021) | SEER 2007-2016 | National | MM 41 789 | OS/multi | Married Not Married | Ref. 1.18 (1.13-1.22)∗ | Unmarried |
| Evans et al,40 (2021) | Institutional 2005-2015 | NS | MM 2543 | OS/multi | Married Unmarried | Ref. 1.32 (1.03-1.69)∗ | Unmarried |
| Costa et al,37 2016 | SEER 2007-2012 | National | MM 10 161 | 1-year mortality | Married Divorced Single Widowed | Ref. 1.31 (1.09-1.58)∗, 1.74 (1.48-2.03)∗, 1.38 (1.01-1.88)∗ | Divorced, single or widowed |
| Ho et al,24 (2017) | CCR 1999-2012 | CA | MM 6359 | 60-day mortality | Married Single | Ref. 1.25 (1.07-1.46)∗ | Single |
| Yung et al,19 (2011) | NYSCR 2001–2008 | NY | AML 3506 | OS/multi | Married Unmarried | Ref. 1.25 (1.07-1.45)∗ | Unmarried |
| CCR 2000–2007 | CA | AML 3506 | OS/multi | Married Unmarried | Ref. 1.31 (1.17-1.48)∗ | Unmarried | |
| Borate et al,38 (2015) | SEER 2007-2011 | National | AML 5541 | OS/multi | Married Single Divorced Widowed | Ref. 1.26 (1.15-1.38)∗, 1.16 (1.04-1.30)∗ 1.14 (0.93-1.41) | Single or divorced |
| OS/multi | Married Divorced Single Widowed | Ref. 1.24 (1.11-1.39)∗, 1.39 (1.27-1.53)∗, 1.43 (1.20-1.71)∗ | Divorced, single, or widowed | ||||
| Perry et al,16 (2017) | SEER 2007-2012 | National | CML 15-64 y.o. 3626 | OS/multi | Married Single Divorced/separated/widowed | Reference 1.65 (1.29-2.13)∗ 1.30 (0.94-1.79) | Single |
| CML 65 y.o. 2142 | OS/multi | Married Single Divorced, separated, or widowed | Ref. 1.15 (0.89-1.48) 1.35 (1.16-1.59)∗ | Divorced, widowed, or separated | |||
| Education: percentage of population without high school degree | |||||||
| Parikh et al,39 (2015) | NCDB 1998-2011 | National | HL 45 777 | OS/uni | ≥ 29% 20%-28.9% 14%-19.9% <14% | Ref. 0.83 (0.78-0.89)∗, 0.78 (0.74-0.83)∗, 0.62 (0.58-0.66)∗ | Higher than 29% |
| OS/multi | ≥ 29% 20%-28.9% 14%-19.9% <14% | Ref. 0.98 (0.86-1.13) 1.14 (0.98-1.32) 0.97 (0.82-1.13) | - | ||||
| Goldstein et al,21 (2019) | NCDB 2004–2014 | National | NHL ≥ 65y.o. 161 | OS/uni | < 7% 7% to 12.9% 13% to 20.9% > 21% | Ref. 1.18 (0.7-2) 1.09 (0.6-1.9) 1.75 (1.3-1) | - |
| Han (2014) | NCDB 2004-2010 | National | NHL 3 858 | OS/multi | < 14% 14%-9.9% 20%-28.9% ≥ 29% | Ref. 1.17 (0.99-1.39) 1.27 (1.07-1.50)†, 1.51 (1.25-1.82)† | Higher than 20% |
| Shah (2019) | NCDB 2004-2013 | National | NHL 18 120 | OS/multi | < 7% ≥ 21% 13%-20% 7%-12.99% | Ref. 1.14 (1.03-1.27)∗, 1.16 (1.07-1.26)∗, 1.12 (1.05-1.20)∗ | Higher than 7% |
| Goldstein et al,21 (2019) | NCDB 2004-2014 | National | NHL < 65 y.o. 22 133 | OS/multi | < 7% 7%-12.9% 13%-20.9% > 21% | Ref. 1.19 (1.05-1.34)∗, 1.40 (1.24-1.59)∗, 1.42 (1.22-1.64)∗ | Higher than 7% |
| NHL ≥ 65 y.o. 21 515 | OS/multi | < 7% 7%-12.9% 13%-20.9% > 21% | Ref. 1.03 (0.96-1.11) 1.09 (1.01-1.18)∗, 1.19 (1.09-1.31)∗ | Higher than 13% | |||
| Dhakal et al,22 (2019) | NCDB 2006-2012 | National | NHL 132 402 | 1-month mortality/Uni | NS | Data not showed | Lower education level |
| Gunaratne et al,35 (2021) | NCBD 2004-2014 | National | WM 3064 | OS/multi | High‡ Middle-2 Middle-1 Low | Ref. 1.16 (0.96-1.4) 1.30 (1.04-1.63) 1.28 (0.97-1.69) | - |
| Chohan et al,18 (2022) | NCDB 2004-2017 | National | WM < 65 y.o. 1249 | OS/uni | ≥ 17.6% 10.9%–17.5% 6.3%–10.8% <6.3% | Ref. 0.90 (0.56-1.43) 0.81 (0.52-1.28) 0.58 (0.36-0.93)∗ | Higher than 17.6% |
| OS/multi | ≥ 17.6% 10.9%–17.5% 6.3%–10.8% <6.3% | Ref. 1.02 (0.59-1.78) 1.02 (0.55-1.88) 0.86 (0.43-1.75) | - | ||||
| WM ≥ 65 y.o. 2629 | OS/multi | ≥ 17.6% 10.9%–17.5% 6.3%–10.8% <6.3% | Ref. 0.97 (0.75-1.26) 0.98 (0.75-1.27) 0.84 (0.72-0.97)∗ | Higher than 17.6% | |||
| Goldstein et al,21 (2019) | NCDB 2004–2014 | National | BL 65 y.o. 5235 | OS/multi | < 7% 7% to 12.9% 13% to 20.9% > 21% | Ref. 1.1 (0.9-1.3) 1.35 (1.1-1.6) 1.39 (1.1-1.7)∗ | Higher than 21% |
| BL ≥ 65 y.o. 1838 | OS/multi | < 7% 7% to 12.9% 13% to 20.9% > 21% | Ref. 0.8 (0.6-1)∗, 0.9 (0.7-1.2)∗, 0.72 (0.5-1)∗ | Higher than 7% | |||
| Evans et al,40 (2021) | Institutional 2005-2015 | NS | MM 2543 | OS/uni | ≤ 7% >7% | Ref. 1.02 (0.88-1.18) | - |
| NCDB 2004-2015 | National | MM 2543 | OS/multi | ≤ 7% >7% | Ref. 1.08 (1.06-1.11)∗ | Higher than 7% | |
| Jayakrishnan (2021) | NCDB 2004-2016 | National | MM 50 543 | OS/multi | ≥ 21% 13.0%-20.9% 7.0%-12.9% < 7.0% | Ref. 0.99 (0.95-1.02) 0.98 (0.94-1.02) 0.94 (0.89-0.99)∗ | Higher than 21% |
| Costa et al,37 (2016) | SEER 2007-2012 | National | MM 10 161 | 12 month- mortality/multi | < 21.3% > 36.8% 29.7%-36.8% 21.3%-29.7% | Ref. 0.92 (0.72-1.17) 1.03 (0.80-1.32) 1.34 (1.05-1.72)∗ | From 21.3% to 29.7% |
| Huang et al,31 (2021) | SEER 2007-2016 | National | MM 17 981 | CSS/uni | 6.83%–21.52% 21.62%–30.99% 31.08%–34.03% 34.07%–41.84% 42.01%–65.45% | Ref. 0.87 (0.80-0.96)∗, 0.87 (0.79-0.95)∗, 0.87 (0.80-0.96)∗, 0.80 (0.73-0.88)∗ | From 68.3% to 21.52% |
| OS/uni | < 21.3% > 36.8% 29.7%-36.8% 21.3%-29.7% | Ref. 1.13 (1.02-1.27)∗, 1.19 (1.07-1.33)∗, 1.46 (1.31-1.62)∗ | Higher than 21.3% | ||||
| CSS/multi | 6.83%–21.52% 21.62%–30.99% 31.08%–34.03% 34.07%–41.84% 42.01%–65.45% | Ref. 0.95 (0.85-1.06) 0.93 (0.82-1.05) 1.02 (0.89-1.17) 0.96 (0.82-1.13) | - | ||||
| OS/uni | 6.83%–21.52% 21.62%–30.99% 31.08%–34.03% 34.07%–41.84% 42.01%–65.45% | Ref. 0.88 (0.81-0.94)∗, 0.91 (0.85-0.98)∗, 0.80 (0.75-0.86)∗, 0.68 (0.63-0.74)∗ | From 6.83% to 21.52% | ||||
| OS/multi | 6.83%–21.52% 21.62%–30.99% 31.08%–34.03% 34.07%–41.84% 42.01%–65.45% | Ref. 0.98 (0.90-1.06) 1.07 (0.97-1.18) 1.02 (0.92-1.14) 0.90 (0.79-1.03) | - | ||||
| Freeman et al,32 (2016) | NC CCR 2003-2009 | NC | AML 900 | OS/multi | NS | 1.00 (0.99-1.02) | - |
| Master et al,28 (2016) | NCDB 1998 -2012 | National | AML. 67 443 | OS/multi | < 14% 14%-19.9% 20%-28.9% ≥ 29% | Ref. 1.03 (1.00-1.06)†, 1.05 (1.02-1.08)† 1.01 (0.97-1.05) | From 14% to 28.9% |
| Borate et al,38 (2015) | SEER 2007-2011 | National | AML 5541 | OS/uni | Quintile 5‡ Quintile1 Quintile 2 Quintile 3 Quintile 4 | Ref. 1.27 (1.13-1.42)∗ 1.17 (1.05-1.31) 1.17 (1.04-1.31) 1.15 (1.02-1.30) | Lower education level |
| Dhakal et al,17 (2022) | NCDB 2004-2015 | National | APL <65 y.o. 5380 | 1-month mortality | <6.3 6.3-10.8 10.9-17.5 ≥17.6 | Ref. 1.18 (0.86-1.61) 1.02 (0.72-1.46) 1.40 (0.96-2.06) | - |
| APL ≥65 y.o. 1520 | 1-month mortality | <6.3 6.3-10.8 10.9-17.5 ≥17.6 | Ref. 1.38- (0.95-2.02) 1.14 (0.73-1.76) 1.18 (0.71-1.97) | - | |||
| APL <65 y.o. 5380 | OS/multi | <6.3 6.3-10.8 10.9-17.5 ≥17.6 | Ref. 0.99 (0.83-1.19) 1.08 (0.89-1.32) 1.14 (0.91-1.43) | - | |||
| APL ≥65 y.o. 1520 | OS/multi | <6.3 6.3-10.8 10.9-17.5 ≥17.6 | Ref. 1.12 (0.91-1.37) 1.12 (0.89-1.41) 1.11 (0.85-1.45) | - | |||
| Perry et al,16 (2017) | SEER 2007-2012 | National | CML 15-64 y.o. 3626 | OS/multi | Below median Above median | Ref. 1.05 (0.73-1.52) | - |
| CML ≥ 65 y.o. 2142 | OS/multi | Below median Above median | Ref. 1.20 (0.94-1.53) | - | |||
| Education: percentage of population without <ninth grade degree | |||||||
| Perry et al,16 (2017) | SEER 2007-2012 | National | CML 15-64 y.o. 3626 | OS/HR | Above median % ninth grade education | NS | - |
| CML ≥ 65 y.o. 2142 | OS/HR | Above median % ninth grade education | NS | - | |||
| Author (year) . | Data source years . | US region . | Patients N . | Outcome/analysis . | Cohorts . | HR (95%-CI) . | Social determinant associated with worse survival . |
|---|---|---|---|---|---|---|---|
| Marital status | |||||||
| Yung et al,19 (2011) | NYSCR 2001–2008 | NY | HL 4752 | OS/multi | Married Unmarried | Ref. 1.49 (1.11-1.99)∗ | Unmarried |
| CCR 2000–2007 | CA | HL 4752 | OS/multi | Married Unmarried | Ref. 1.26 (0.97-1.64) | - | |
| Tao et al,25 (2014) | CCR 2001-2009 | CA | NHL 16 133 | CSS/multi | Married Never married Previously married | Ref. 1.13 (1.07-1.20)∗, 1.13 (1.09-1.18)∗ | Unmarried |
| Huang et al,31 (2021) | SEER 2007-2016 | National | MM 17 981 | CSS/multi | Married Single | Ref. 1.15 (1.06-1.24)∗ | Single |
| OS/multi | Married Single Other | Ref. 1.29 (1.22-1.38)∗, 1.35 (1.26-1.44)∗ | Single, divorced, separated, domestic partner, or widowed | ||||
| Makhani (2021) | SEER 2007-2016 | National | MM 41 789 | OS/multi | Married Not Married | Ref. 1.18 (1.13-1.22)∗ | Unmarried |
| Evans et al,40 (2021) | Institutional 2005-2015 | NS | MM 2543 | OS/multi | Married Unmarried | Ref. 1.32 (1.03-1.69)∗ | Unmarried |
| Costa et al,37 2016 | SEER 2007-2012 | National | MM 10 161 | 1-year mortality | Married Divorced Single Widowed | Ref. 1.31 (1.09-1.58)∗, 1.74 (1.48-2.03)∗, 1.38 (1.01-1.88)∗ | Divorced, single or widowed |
| Ho et al,24 (2017) | CCR 1999-2012 | CA | MM 6359 | 60-day mortality | Married Single | Ref. 1.25 (1.07-1.46)∗ | Single |
| Yung et al,19 (2011) | NYSCR 2001–2008 | NY | AML 3506 | OS/multi | Married Unmarried | Ref. 1.25 (1.07-1.45)∗ | Unmarried |
| CCR 2000–2007 | CA | AML 3506 | OS/multi | Married Unmarried | Ref. 1.31 (1.17-1.48)∗ | Unmarried | |
| Borate et al,38 (2015) | SEER 2007-2011 | National | AML 5541 | OS/multi | Married Single Divorced Widowed | Ref. 1.26 (1.15-1.38)∗, 1.16 (1.04-1.30)∗ 1.14 (0.93-1.41) | Single or divorced |
| OS/multi | Married Divorced Single Widowed | Ref. 1.24 (1.11-1.39)∗, 1.39 (1.27-1.53)∗, 1.43 (1.20-1.71)∗ | Divorced, single, or widowed | ||||
| Perry et al,16 (2017) | SEER 2007-2012 | National | CML 15-64 y.o. 3626 | OS/multi | Married Single Divorced/separated/widowed | Reference 1.65 (1.29-2.13)∗ 1.30 (0.94-1.79) | Single |
| CML 65 y.o. 2142 | OS/multi | Married Single Divorced, separated, or widowed | Ref. 1.15 (0.89-1.48) 1.35 (1.16-1.59)∗ | Divorced, widowed, or separated | |||
| Education: percentage of population without high school degree | |||||||
| Parikh et al,39 (2015) | NCDB 1998-2011 | National | HL 45 777 | OS/uni | ≥ 29% 20%-28.9% 14%-19.9% <14% | Ref. 0.83 (0.78-0.89)∗, 0.78 (0.74-0.83)∗, 0.62 (0.58-0.66)∗ | Higher than 29% |
| OS/multi | ≥ 29% 20%-28.9% 14%-19.9% <14% | Ref. 0.98 (0.86-1.13) 1.14 (0.98-1.32) 0.97 (0.82-1.13) | - | ||||
| Goldstein et al,21 (2019) | NCDB 2004–2014 | National | NHL ≥ 65y.o. 161 | OS/uni | < 7% 7% to 12.9% 13% to 20.9% > 21% | Ref. 1.18 (0.7-2) 1.09 (0.6-1.9) 1.75 (1.3-1) | - |
| Han (2014) | NCDB 2004-2010 | National | NHL 3 858 | OS/multi | < 14% 14%-9.9% 20%-28.9% ≥ 29% | Ref. 1.17 (0.99-1.39) 1.27 (1.07-1.50)†, 1.51 (1.25-1.82)† | Higher than 20% |
| Shah (2019) | NCDB 2004-2013 | National | NHL 18 120 | OS/multi | < 7% ≥ 21% 13%-20% 7%-12.99% | Ref. 1.14 (1.03-1.27)∗, 1.16 (1.07-1.26)∗, 1.12 (1.05-1.20)∗ | Higher than 7% |
| Goldstein et al,21 (2019) | NCDB 2004-2014 | National | NHL < 65 y.o. 22 133 | OS/multi | < 7% 7%-12.9% 13%-20.9% > 21% | Ref. 1.19 (1.05-1.34)∗, 1.40 (1.24-1.59)∗, 1.42 (1.22-1.64)∗ | Higher than 7% |
| NHL ≥ 65 y.o. 21 515 | OS/multi | < 7% 7%-12.9% 13%-20.9% > 21% | Ref. 1.03 (0.96-1.11) 1.09 (1.01-1.18)∗, 1.19 (1.09-1.31)∗ | Higher than 13% | |||
| Dhakal et al,22 (2019) | NCDB 2006-2012 | National | NHL 132 402 | 1-month mortality/Uni | NS | Data not showed | Lower education level |
| Gunaratne et al,35 (2021) | NCBD 2004-2014 | National | WM 3064 | OS/multi | High‡ Middle-2 Middle-1 Low | Ref. 1.16 (0.96-1.4) 1.30 (1.04-1.63) 1.28 (0.97-1.69) | - |
| Chohan et al,18 (2022) | NCDB 2004-2017 | National | WM < 65 y.o. 1249 | OS/uni | ≥ 17.6% 10.9%–17.5% 6.3%–10.8% <6.3% | Ref. 0.90 (0.56-1.43) 0.81 (0.52-1.28) 0.58 (0.36-0.93)∗ | Higher than 17.6% |
| OS/multi | ≥ 17.6% 10.9%–17.5% 6.3%–10.8% <6.3% | Ref. 1.02 (0.59-1.78) 1.02 (0.55-1.88) 0.86 (0.43-1.75) | - | ||||
| WM ≥ 65 y.o. 2629 | OS/multi | ≥ 17.6% 10.9%–17.5% 6.3%–10.8% <6.3% | Ref. 0.97 (0.75-1.26) 0.98 (0.75-1.27) 0.84 (0.72-0.97)∗ | Higher than 17.6% | |||
| Goldstein et al,21 (2019) | NCDB 2004–2014 | National | BL 65 y.o. 5235 | OS/multi | < 7% 7% to 12.9% 13% to 20.9% > 21% | Ref. 1.1 (0.9-1.3) 1.35 (1.1-1.6) 1.39 (1.1-1.7)∗ | Higher than 21% |
| BL ≥ 65 y.o. 1838 | OS/multi | < 7% 7% to 12.9% 13% to 20.9% > 21% | Ref. 0.8 (0.6-1)∗, 0.9 (0.7-1.2)∗, 0.72 (0.5-1)∗ | Higher than 7% | |||
| Evans et al,40 (2021) | Institutional 2005-2015 | NS | MM 2543 | OS/uni | ≤ 7% >7% | Ref. 1.02 (0.88-1.18) | - |
| NCDB 2004-2015 | National | MM 2543 | OS/multi | ≤ 7% >7% | Ref. 1.08 (1.06-1.11)∗ | Higher than 7% | |
| Jayakrishnan (2021) | NCDB 2004-2016 | National | MM 50 543 | OS/multi | ≥ 21% 13.0%-20.9% 7.0%-12.9% < 7.0% | Ref. 0.99 (0.95-1.02) 0.98 (0.94-1.02) 0.94 (0.89-0.99)∗ | Higher than 21% |
| Costa et al,37 (2016) | SEER 2007-2012 | National | MM 10 161 | 12 month- mortality/multi | < 21.3% > 36.8% 29.7%-36.8% 21.3%-29.7% | Ref. 0.92 (0.72-1.17) 1.03 (0.80-1.32) 1.34 (1.05-1.72)∗ | From 21.3% to 29.7% |
| Huang et al,31 (2021) | SEER 2007-2016 | National | MM 17 981 | CSS/uni | 6.83%–21.52% 21.62%–30.99% 31.08%–34.03% 34.07%–41.84% 42.01%–65.45% | Ref. 0.87 (0.80-0.96)∗, 0.87 (0.79-0.95)∗, 0.87 (0.80-0.96)∗, 0.80 (0.73-0.88)∗ | From 68.3% to 21.52% |
| OS/uni | < 21.3% > 36.8% 29.7%-36.8% 21.3%-29.7% | Ref. 1.13 (1.02-1.27)∗, 1.19 (1.07-1.33)∗, 1.46 (1.31-1.62)∗ | Higher than 21.3% | ||||
| CSS/multi | 6.83%–21.52% 21.62%–30.99% 31.08%–34.03% 34.07%–41.84% 42.01%–65.45% | Ref. 0.95 (0.85-1.06) 0.93 (0.82-1.05) 1.02 (0.89-1.17) 0.96 (0.82-1.13) | - | ||||
| OS/uni | 6.83%–21.52% 21.62%–30.99% 31.08%–34.03% 34.07%–41.84% 42.01%–65.45% | Ref. 0.88 (0.81-0.94)∗, 0.91 (0.85-0.98)∗, 0.80 (0.75-0.86)∗, 0.68 (0.63-0.74)∗ | From 6.83% to 21.52% | ||||
| OS/multi | 6.83%–21.52% 21.62%–30.99% 31.08%–34.03% 34.07%–41.84% 42.01%–65.45% | Ref. 0.98 (0.90-1.06) 1.07 (0.97-1.18) 1.02 (0.92-1.14) 0.90 (0.79-1.03) | - | ||||
| Freeman et al,32 (2016) | NC CCR 2003-2009 | NC | AML 900 | OS/multi | NS | 1.00 (0.99-1.02) | - |
| Master et al,28 (2016) | NCDB 1998 -2012 | National | AML. 67 443 | OS/multi | < 14% 14%-19.9% 20%-28.9% ≥ 29% | Ref. 1.03 (1.00-1.06)†, 1.05 (1.02-1.08)† 1.01 (0.97-1.05) | From 14% to 28.9% |
| Borate et al,38 (2015) | SEER 2007-2011 | National | AML 5541 | OS/uni | Quintile 5‡ Quintile1 Quintile 2 Quintile 3 Quintile 4 | Ref. 1.27 (1.13-1.42)∗ 1.17 (1.05-1.31) 1.17 (1.04-1.31) 1.15 (1.02-1.30) | Lower education level |
| Dhakal et al,17 (2022) | NCDB 2004-2015 | National | APL <65 y.o. 5380 | 1-month mortality | <6.3 6.3-10.8 10.9-17.5 ≥17.6 | Ref. 1.18 (0.86-1.61) 1.02 (0.72-1.46) 1.40 (0.96-2.06) | - |
| APL ≥65 y.o. 1520 | 1-month mortality | <6.3 6.3-10.8 10.9-17.5 ≥17.6 | Ref. 1.38- (0.95-2.02) 1.14 (0.73-1.76) 1.18 (0.71-1.97) | - | |||
| APL <65 y.o. 5380 | OS/multi | <6.3 6.3-10.8 10.9-17.5 ≥17.6 | Ref. 0.99 (0.83-1.19) 1.08 (0.89-1.32) 1.14 (0.91-1.43) | - | |||
| APL ≥65 y.o. 1520 | OS/multi | <6.3 6.3-10.8 10.9-17.5 ≥17.6 | Ref. 1.12 (0.91-1.37) 1.12 (0.89-1.41) 1.11 (0.85-1.45) | - | |||
| Perry et al,16 (2017) | SEER 2007-2012 | National | CML 15-64 y.o. 3626 | OS/multi | Below median Above median | Ref. 1.05 (0.73-1.52) | - |
| CML ≥ 65 y.o. 2142 | OS/multi | Below median Above median | Ref. 1.20 (0.94-1.53) | - | |||
| Education: percentage of population without <ninth grade degree | |||||||
| Perry et al,16 (2017) | SEER 2007-2012 | National | CML 15-64 y.o. 3626 | OS/HR | Above median % ninth grade education | NS | - |
| CML ≥ 65 y.o. 2142 | OS/HR | Above median % ninth grade education | NS | - | |||
AML, acute myeloid leukemia; APL, acute promyelocytic leukemia; BL, Burkitt lymphoma; CA, California; CCR, California Cancer Registry; CI, confidential interval; CML, chronic myeloid leukemia; CSS, cancer-specific survival; HL, Hodgkin lymphoma; HR, hazard ratio; MM, multiple myeloma; multi, multivariate analysis; N, sample size; NC, North Carolina; NCDB, National Cancer Database; NC CCR, North Carolina Central Cancer Registry; NHL, non-Hodgkin lymphoma; NOS, not otherwise specified; NS, not specified; NY, New York; NYSCR, New York state cancer registry; Ref., Reference; SEER, Surveillance, Epidemiology, and End Results Registry; uni, univariate analysis; WM, Waldenstrom macroglobulinemia; y.o., years old.
Reported as statistical significance by the author.
Statistical significance but not discussed by the author.
Not specified values.