Table 3.

Neuropathy management strategies in patients receiving BV + AVD

Treatment modificationOverall (n = 153), n (%)
BV modification 67 (44%) 
Dose reduction 26 (17%) 
Discontinuation 19 (12%) 
Dose reduction followed by discontinuation 16 (11%) 
Dose hold followed by dose reduction 6 (4%) 
Vinblastine modification 26 (17%) 
Hold or discontinuation 16 (10%) 
Dose reduction 10 (7%) 
BV continued 9 (6%) 
Treatment modificationOverall (n = 153), n (%)
BV modification 67 (44%) 
Dose reduction 26 (17%) 
Discontinuation 19 (12%) 
Dose reduction followed by discontinuation 16 (11%) 
Dose hold followed by dose reduction 6 (4%) 
Vinblastine modification 26 (17%) 
Hold or discontinuation 16 (10%) 
Dose reduction 10 (7%) 
BV continued 9 (6%) 

Because BV modification was our primary interest, more granular data were collected about discontinuation and dose reduction and the temporal relationship between these events than for vinblastine.

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