Incidence and characteristics of neuropathy from BV + AVD
| Characteristic . | Overall (n=153), n (%) . |
|---|---|
| Any neuropathy | 123 (80%) |
| Maximal grade | |
| 1 | 60 (39%) |
| 2 | 47 (31%) |
| 3 | 15 (10%) |
| Distribution | |
| Sensory only | 84 (55%) |
| Motor only | 1 (1%) |
| Mixed sensory and motor | 29 (19%) |
| Unknown | 9 (6%) |
| Median time to onset, mo (range) | 2 (0.23-13) |
| Characteristic . | Overall (n=153), n (%) . |
|---|---|
| Any neuropathy | 123 (80%) |
| Maximal grade | |
| 1 | 60 (39%) |
| 2 | 47 (31%) |
| 3 | 15 (10%) |
| Distribution | |
| Sensory only | 84 (55%) |
| Motor only | 1 (1%) |
| Mixed sensory and motor | 29 (19%) |
| Unknown | 9 (6%) |
| Median time to onset, mo (range) | 2 (0.23-13) |
Neuropathy was graded retrospectively using modified CTCAE v5.0 criteria (grade 1: asymptomatic or mild symptoms, including paresthesias or observed decreased deep tendon reflexes; grade 2: moderate symptoms, limiting function or instrumental activity of daily living (ADL); grade 3: severe symptoms, limiting self-care ADL).