Causes of thrombocytosis
| Reactive |
| Iron deficiency |
| Blood loss |
| Surgery |
| Acute bacterial infection |
| Chronic inflammation (eg, vasculitis, rheumatoid arthritis, chronic infection, inflammatory bowel disease) |
| Nonmyeloid malignancies (eg, lung, colorectal) |
| Splenectomy/hyposplenism |
| Clonal myeloid disorders |
| MPNs |
| ET |
| PV |
| Primary myelofibrosis |
| Chronic myeloid leukemia |
| MPN, not otherwise specified |
| MDS/MPNs |
| MDS/MPN with SF3B1 mutation and thrombocytosis |
| MDS/MPN, not otherwise specified |
| Myelodysplastic neoplasms |
| MDS with low blasts and isolated 5q deletion |
| Reactive |
| Iron deficiency |
| Blood loss |
| Surgery |
| Acute bacterial infection |
| Chronic inflammation (eg, vasculitis, rheumatoid arthritis, chronic infection, inflammatory bowel disease) |
| Nonmyeloid malignancies (eg, lung, colorectal) |
| Splenectomy/hyposplenism |
| Clonal myeloid disorders |
| MPNs |
| ET |
| PV |
| Primary myelofibrosis |
| Chronic myeloid leukemia |
| MPN, not otherwise specified |
| MDS/MPNs |
| MDS/MPN with SF3B1 mutation and thrombocytosis |
| MDS/MPN, not otherwise specified |
| Myelodysplastic neoplasms |
| MDS with low blasts and isolated 5q deletion |