Treatment-emergent grade 3 to 4 AEs (safety-evaluable population)
| Most common AEs,∗ n (%) . | Pola-R-CHP (n = 140) . | R-CHOP (n = 139) . |
|---|---|---|
| Neutropenia | 42 (30.0) | 37 (26.6) |
| Neutrophil count decreased† | 42 (30.0) | 34 (24.5) |
| White blood cell count decreased† | 38 (27.1) | 29 (20.9) |
| Leukopenia | 23 (16.4) | 23 (16.5) |
| Febrile neutropenia | 17 (12.1) | 14 (10.1) |
| Anemia | 12 (8.6) | 17 (12.2) |
| Lymphocyte count decreased† | 15 (10.7) | 12 (8.6) |
| Platelet count decreased | 9 (6.4) | 11 (7.9) |
| Pneumonia | 9 (6.4) | 10 (7.2) |
| Most common AEs,∗ n (%) . | Pola-R-CHP (n = 140) . | R-CHOP (n = 139) . |
|---|---|---|
| Neutropenia | 42 (30.0) | 37 (26.6) |
| Neutrophil count decreased† | 42 (30.0) | 34 (24.5) |
| White blood cell count decreased† | 38 (27.1) | 29 (20.9) |
| Leukopenia | 23 (16.4) | 23 (16.5) |
| Febrile neutropenia | 17 (12.1) | 14 (10.1) |
| Anemia | 12 (8.6) | 17 (12.2) |
| Lymphocyte count decreased† | 15 (10.7) | 12 (8.6) |
| Platelet count decreased | 9 (6.4) | 11 (7.9) |
| Pneumonia | 9 (6.4) | 10 (7.2) |
AEs are MedDRA version 24.0 preferred terms.
MedDRA, the Medical Dictionary for Regulatory Activities.
Most common was defined as grade 3 to 4 AEs occurring in ≥5% of patients in any treatment arm.
Finding based on laboratory test results indicating a decrease in the number of white blood cells in a blood specimen.