Table 1.

Baseline clinical and genetic characteristics of patients in the MyXI trial

CharacteristicNN = 556 
Age, y 556 59 (54-64) 
Male 556 360 (65) 
World Health Organization performance status 534  
 233 (44) 
 214 (40) 
 65 (12) 
≥3  22 (4.1) 
Unknown  22 
International Staging System 519  
 167 (32) 
 240 (46) 
 112 (22) 
Unknown  37 
Revised International Staging System 445  
 78 (17) 
 314 (71) 
 53 (12) 
Unknown   111 
Kappa light chain restriction 553 363 (66) 
Unknown  
Induction randomization 556  
KCRD  122 (22) 
CTD  210 (38) 
CRD  224 (40) 
Maintenance randomization 556  
Len  359 (65) 
Observation  197 (35) 
t(4;14) 556 76 (14) 
t(14;16)/t(14;20) 556 20 (3.6) 
del(1p) 556 56 (10) 
del(17p) 556 46 (8.3) 
gain(1q) 556 185 (33) 
CharacteristicNN = 556 
Age, y 556 59 (54-64) 
Male 556 360 (65) 
World Health Organization performance status 534  
 233 (44) 
 214 (40) 
 65 (12) 
≥3  22 (4.1) 
Unknown  22 
International Staging System 519  
 167 (32) 
 240 (46) 
 112 (22) 
Unknown  37 
Revised International Staging System 445  
 78 (17) 
 314 (71) 
 53 (12) 
Unknown   111 
Kappa light chain restriction 553 363 (66) 
Unknown  
Induction randomization 556  
KCRD  122 (22) 
CTD  210 (38) 
CRD  224 (40) 
Maintenance randomization 556  
Len  359 (65) 
Observation  197 (35) 
t(4;14) 556 76 (14) 
t(14;16)/t(14;20) 556 20 (3.6) 
del(1p) 556 56 (10) 
del(17p) 556 46 (8.3) 
gain(1q) 556 185 (33) 

CTD, cyclophosphamide, dexamethasone combined with thalidomide; CRD, cyclophosphamide, Len, and dexamethasone; KCRD, carfilzomib combined with CRD.

Statistics presented: median (interquartile range) or n (%).

Main reason for missingness is missing lactate dehydrogenase test.

Close Modal

or Create an Account

Close Modal
Close Modal