Incidence rate of unplanned hospitalizations in patients newly diagnosed with MM treated with VRd vs Rd, based on frailty severity and in combined overall population after matching for stage and PS within frailty categories
| Population . | Incidence rate per 5 person-years (95% CI) . | Incidence rate ratio (95% CI) . | |
|---|---|---|---|
| VRd . | Rd . | ||
| Moderate-severe frailty (VA-FI ≥ 0.3) | 1.36 (1.21-1.54) | 1.19 (1.05-1.35) | 1.14 (0.96-1.36) |
| Mild frailty (VA-FI = 0.2-0.3) | 1.44 (1.26-1.65) | 1.13 (0.99-1.29) | 1.27 (1.06-1.54) |
| Nonfrail (VA-FI < 0.2) | 1.51 (1.34-1.69) | 1.21 (1.08-1.35) | 1.24 (1.06-1.46) |
| Overall | 1.44 (1.34-1.54) | 1.18 (1.1-1.27) | 1.22 (1.10-1.34) |
| Population . | Incidence rate per 5 person-years (95% CI) . | Incidence rate ratio (95% CI) . | |
|---|---|---|---|
| VRd . | Rd . | ||
| Moderate-severe frailty (VA-FI ≥ 0.3) | 1.36 (1.21-1.54) | 1.19 (1.05-1.35) | 1.14 (0.96-1.36) |
| Mild frailty (VA-FI = 0.2-0.3) | 1.44 (1.26-1.65) | 1.13 (0.99-1.29) | 1.27 (1.06-1.54) |
| Nonfrail (VA-FI < 0.2) | 1.51 (1.34-1.69) | 1.21 (1.08-1.35) | 1.24 (1.06-1.46) |
| Overall | 1.44 (1.34-1.54) | 1.18 (1.1-1.27) | 1.22 (1.10-1.34) |