Adjusted ORs for bleeding in all (HHT and non-HHT), using multivariable logistic regression∗
| Variable . | OR . | 95% CIs . | P value . |
|---|---|---|---|
| PUD | 25.43 | 25.11-25.75 | < .001 |
| HHT | 5.47 | 4.93-6.06 | < .001 |
| Portal HTN | 2.59 | 2.53-2.64 | < .001 |
| Liver disease | Omnibus P < .001 | ||
| No liver disease | Reference | ||
| Mild liver disease | 2.38 | 2.33-2.43 | < .001 |
| Moderate or severe liver disease | 2.32 | 2.27-2.37 | < .001 |
| Cirrhosis | 2.10 | 2.06-2.13 | < .001 |
| PVT | 1.54 | 1.48-1.60 | < .001 |
| Female (ref = male) | 1.15 | 1.14-1.16 | < .001 |
| Race | Omnibus P < .001 | ||
| Caucasian | Reference | ||
| Asian | 1.13 | 1.11-1.16 | < .001 |
| African American | 1.12 | 1.11-1.13 | < .001 |
| Other | 1.08 | 1.07-1.09 | < .001 |
| Malignancy | 1.11 | 1.10-1.13 | < .000 |
| Peripheral vascular disease | 1.11 | 1.10-1.12 | < .001 |
| Age per 10 y (continuous) | 1.09 | 1.09-1.10 | < .001 |
| Charlson comorbidity score | 1.02 | 1.02-1.02 | < .001 |
| HCV | 1.00 | 0.98-1.03 | .709 |
| HTN | 1.00 | 0.99-1.00 | < .001 |
| Chronic pulmonary disease | 0.92 | 0.91-0.92 | < .001 |
| Variable . | OR . | 95% CIs . | P value . |
|---|---|---|---|
| PUD | 25.43 | 25.11-25.75 | < .001 |
| HHT | 5.47 | 4.93-6.06 | < .001 |
| Portal HTN | 2.59 | 2.53-2.64 | < .001 |
| Liver disease | Omnibus P < .001 | ||
| No liver disease | Reference | ||
| Mild liver disease | 2.38 | 2.33-2.43 | < .001 |
| Moderate or severe liver disease | 2.32 | 2.27-2.37 | < .001 |
| Cirrhosis | 2.10 | 2.06-2.13 | < .001 |
| PVT | 1.54 | 1.48-1.60 | < .001 |
| Female (ref = male) | 1.15 | 1.14-1.16 | < .001 |
| Race | Omnibus P < .001 | ||
| Caucasian | Reference | ||
| Asian | 1.13 | 1.11-1.16 | < .001 |
| African American | 1.12 | 1.11-1.13 | < .001 |
| Other | 1.08 | 1.07-1.09 | < .001 |
| Malignancy | 1.11 | 1.10-1.13 | < .000 |
| Peripheral vascular disease | 1.11 | 1.10-1.12 | < .001 |
| Age per 10 y (continuous) | 1.09 | 1.09-1.10 | < .001 |
| Charlson comorbidity score | 1.02 | 1.02-1.02 | < .001 |
| HCV | 1.00 | 0.98-1.03 | .709 |
| HTN | 1.00 | 0.99-1.00 | < .001 |
| Chronic pulmonary disease | 0.92 | 0.91-0.92 | < .001 |
Adjusted for age and other covariates.