Table 4.

Adjusted ORs for bleeding in HHT by multivariable logistic regression

VariableOR95% CIsP value
PUD 8.86 5.11-15.38 < .001 
PVT 3.68 1.44-9.36 .006 
HCV 2.13 1.14-3.98 .017 
Liver disease   Omnibus P = .116 
No liver disease Reference  
Cirrhosis 1.54 1.01-2.34 .044 
Moderate or severe liver disease 2.01 0.97-4.17 .061 
Mild liver disease 0.81 0.36-1.80 .603 
Peripheral vascular disease 1.31 0.88-1.96 .190 
Race   Omnibus P = .222 
Caucasian Reference  
African American 1.31 0.99-1.74 .060 
Asian 0.82 0.28-2.43 .727 
Other 1.19 0.87-1.63 .268 
Portal HTN 1.28 0.68-2.41 .436 
HTN 1.26 1.02-1.56 .030 
Charlson comorbidity score 1.00 0.94-1.06 .986 
Age per 10 y (continuous) 0.98 0.92-1.05 .634 
Female (ref = male) 0.82 0.67-1.00 .048 
Chronic pulmonary disease 0.79 0.62-1.00 .046 
Malignancy 0.60 0.37-0.96 .035 
VariableOR95% CIsP value
PUD 8.86 5.11-15.38 < .001 
PVT 3.68 1.44-9.36 .006 
HCV 2.13 1.14-3.98 .017 
Liver disease   Omnibus P = .116 
No liver disease Reference  
Cirrhosis 1.54 1.01-2.34 .044 
Moderate or severe liver disease 2.01 0.97-4.17 .061 
Mild liver disease 0.81 0.36-1.80 .603 
Peripheral vascular disease 1.31 0.88-1.96 .190 
Race   Omnibus P = .222 
Caucasian Reference  
African American 1.31 0.99-1.74 .060 
Asian 0.82 0.28-2.43 .727 
Other 1.19 0.87-1.63 .268 
Portal HTN 1.28 0.68-2.41 .436 
HTN 1.26 1.02-1.56 .030 
Charlson comorbidity score 1.00 0.94-1.06 .986 
Age per 10 y (continuous) 0.98 0.92-1.05 .634 
Female (ref = male) 0.82 0.67-1.00 .048 
Chronic pulmonary disease 0.79 0.62-1.00 .046 
Malignancy 0.60 0.37-0.96 .035 
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