Patient, donor, and graft characteristics
| Variable . | Entire cohort (n = 32) . |
|---|---|
| Sex, n (%) | |
| Male | 18 (59) |
| Female | 14 (41) |
| Median age, Y (range) | |
| Recipient | 12 (1-23) |
| Donor | 35 (4-53) |
| MRD results, n (%) | |
| Negative | 22 (69) |
| Positive | 10 (31) |
| DRI, n (%) | |
| Low/intermediate | 17 (53) |
| High | 15 (47) |
| Diagnosis, n (%) | |
| AML | 15 (47) |
| MDS | 5 (16) |
| ALL | 11 (34) |
| Mixed lineage | 1 (3) |
| Donor relation, n (%) | |
| Sibling | 8 (25) |
| Parent | 24 (75) |
| HLA alleles, n (range) | |
| Median HLA match | 5/10 (5-8/10) |
| No. of HLA alleles match | n (%) |
| 8/10 | 2 (6) |
| 7/10 | 2 (6) |
| 6/10 | 6 (19) |
| 5/10 | 22 (69) |
| Cell dose infused, n (range) | |
| TNC/kg BM infused | 4.8 × 108 (1.2 × 108-6.8 × 108) |
| CD34+/kg BM infused | 4.3 × 106 (0.9 × 106-9.3 × 106) |
| Conditioning regimen, n (%) | |
| Bu/Cy | 20 (62) |
| Cy/TBI | 12 (38) |
| Variable . | Entire cohort (n = 32) . |
|---|---|
| Sex, n (%) | |
| Male | 18 (59) |
| Female | 14 (41) |
| Median age, Y (range) | |
| Recipient | 12 (1-23) |
| Donor | 35 (4-53) |
| MRD results, n (%) | |
| Negative | 22 (69) |
| Positive | 10 (31) |
| DRI, n (%) | |
| Low/intermediate | 17 (53) |
| High | 15 (47) |
| Diagnosis, n (%) | |
| AML | 15 (47) |
| MDS | 5 (16) |
| ALL | 11 (34) |
| Mixed lineage | 1 (3) |
| Donor relation, n (%) | |
| Sibling | 8 (25) |
| Parent | 24 (75) |
| HLA alleles, n (range) | |
| Median HLA match | 5/10 (5-8/10) |
| No. of HLA alleles match | n (%) |
| 8/10 | 2 (6) |
| 7/10 | 2 (6) |
| 6/10 | 6 (19) |
| 5/10 | 22 (69) |
| Cell dose infused, n (range) | |
| TNC/kg BM infused | 4.8 × 108 (1.2 × 108-6.8 × 108) |
| CD34+/kg BM infused | 4.3 × 106 (0.9 × 106-9.3 × 106) |
| Conditioning regimen, n (%) | |
| Bu/Cy | 20 (62) |
| Cy/TBI | 12 (38) |