Characteristics of the UK Biobank study
| . | Men . | Women . | Combined . | |||
|---|---|---|---|---|---|---|
| Cases . | Controls . | Cases . | Controls . | Cases . | Controls . | |
| N (% male) | 4440 (100) | 135 222 (100) | 6346 (0) | 149 902 (0) | 10 786 (41.2) | 285 124 (47.4) |
| Age (y) | 59.5 (7.4) | 57.0 (8.1) | 59.1 (7.3) | 56.6 (7.9) | 59.2 (7.4) | 56.8 (8.0) |
| BMI (Kg/m2) | 29.5 (5.1) | 27.8 (4.2) | 27.3 (5.4) | 26.9 (5.0) | 29.3 (5.7) | 27.3 (4.7) |
| Ever Smoker | 2608 (59.0) | 69 459 (51.6) | 2790 (44.2) | 60 051 (40.2) | 5398 (50.3) | 129 510 (45.6) |
| Oral contraceptives | 58 (0.9) | 3586 (2.4) | 58 (0.9) | 3586 (2.4) | ||
| HRT | 394 (6.3) | 10 224 (6.9) | 394 (6.3) | 10 224 (6.9) | ||
| PE | 1558 (35.1) | 1910 (30.1) | 3468 (32.2) | |||
| Age at PE diagnosis | 48.8 (12.1) | 43.4 (13.2) | 45.8 (13.0) | |||
| DVT | 3479 (78.4) | 5017 (79.1) | 8496 (78.8) | |||
| Age at DVT diagnosis | 48.4 (11.9) | 39.3 (13.7) | 43.0 (13.8) | |||
| DVT and PE | 597 (13.4) | 581 (9.1) | 1178 (10.9) | |||
| MDD | 177 (4.2) | 6184 (4.8) | 531 (8.8) | 12 977 (9.1) | 708 (6.9) | 19 161 (7.1) |
| BD | 18 (0.4) | 602 (0.5) | 32 (0.5) | 617 (0.4) | 50 (0.5) | 1219 (0.4) |
| GAD | 56 (7.7) | 1908 (6.4) | 189 (17.6) | 3615 (11.4) | 245 (13.6) | 5523 (9.0) |
| . | Men . | Women . | Combined . | |||
|---|---|---|---|---|---|---|
| Cases . | Controls . | Cases . | Controls . | Cases . | Controls . | |
| N (% male) | 4440 (100) | 135 222 (100) | 6346 (0) | 149 902 (0) | 10 786 (41.2) | 285 124 (47.4) |
| Age (y) | 59.5 (7.4) | 57.0 (8.1) | 59.1 (7.3) | 56.6 (7.9) | 59.2 (7.4) | 56.8 (8.0) |
| BMI (Kg/m2) | 29.5 (5.1) | 27.8 (4.2) | 27.3 (5.4) | 26.9 (5.0) | 29.3 (5.7) | 27.3 (4.7) |
| Ever Smoker | 2608 (59.0) | 69 459 (51.6) | 2790 (44.2) | 60 051 (40.2) | 5398 (50.3) | 129 510 (45.6) |
| Oral contraceptives | 58 (0.9) | 3586 (2.4) | 58 (0.9) | 3586 (2.4) | ||
| HRT | 394 (6.3) | 10 224 (6.9) | 394 (6.3) | 10 224 (6.9) | ||
| PE | 1558 (35.1) | 1910 (30.1) | 3468 (32.2) | |||
| Age at PE diagnosis | 48.8 (12.1) | 43.4 (13.2) | 45.8 (13.0) | |||
| DVT | 3479 (78.4) | 5017 (79.1) | 8496 (78.8) | |||
| Age at DVT diagnosis | 48.4 (11.9) | 39.3 (13.7) | 43.0 (13.8) | |||
| DVT and PE | 597 (13.4) | 581 (9.1) | 1178 (10.9) | |||
| MDD | 177 (4.2) | 6184 (4.8) | 531 (8.8) | 12 977 (9.1) | 708 (6.9) | 19 161 (7.1) |
| BD | 18 (0.4) | 602 (0.5) | 32 (0.5) | 617 (0.4) | 50 (0.5) | 1219 (0.4) |
| GAD | 56 (7.7) | 1908 (6.4) | 189 (17.6) | 3615 (11.4) | 245 (13.6) | 5523 (9.0) |
Continuous variables are presented as mean (standard deviation) and categorical variables are presented as number (percentage).
GAD, generalized anxiety disorder; HRT, hormone replacement therapy.