Baseline patient demographics
| . | MAC . | RIC . |
|---|---|---|
| N | 32 | 46 |
| Male, N (%) | 21 (65.6) | 31 (67.4) |
| Female, N (%) | 11 (34.4) | 15 (32.6) |
| Age (med) (y) (Min-Max) | 38.0 (18-59) | 59.0 (20-69) |
| Diagnoses | ||
| AML | 14 (43.8) | 25 (54.3) |
| CR1 | 8 | 13 |
| CR2 | 6 | 11 |
| ALL | 9 (28.1) | 3 (6.5) |
| CR1 | 7 | 1 |
| CR2 | 2 | 2 |
| CML | 1 (3.1) | 0 (0.0) |
| MDS | 3 (9.3) | 2 (4.3) |
| NHL | 3 (9.3) | 7 (15.2) |
| CR1 | 0 | 1 |
| CR2 | 1 | 1 |
| >CR2 | 2 | 5 |
| HL | 0 | 4 (8.7) |
| CR1 | — | 0 |
| CR2 | — | 2 |
| >CR2 | — | 2 |
| MPD/MM/other | 2 (6.2) | 5 (10.9) |
| DRI | ||
| Low | 4 (12.5) | 11 (24.4) |
| Intermediate | 24 (75) | 26 (57.8) |
| High | 4 (12.5) | 8 (17.8) |
| HCT-CI | ||
| <3 | 32(100) | 36 (78.3) |
| ≥3 | 0(0) | 10(21.7) |
| Karnofsky performance status (%) | ||
| ≥90 | 83.4 | 60.8 |
| <90 | 17.6 | 39.2 |
| Previous auto HSCT | 3 (9.4) | 6 (13) |
| CMV serology | ||
| Positive | 25 (78.1) | 39 (84.8) |
| Negative | 7 (21.9) | 7 (15.2) |
| Donor age (med) (y) (min-max) | 28.5 (14-65) | 34.5 (21-68) |
| Donor relation | ||
| Offspring | 7 | 27 |
| Sibling | 22 | 17 |
| Parent | 3 | 1 |
| . | MAC . | RIC . |
|---|---|---|
| N | 32 | 46 |
| Male, N (%) | 21 (65.6) | 31 (67.4) |
| Female, N (%) | 11 (34.4) | 15 (32.6) |
| Age (med) (y) (Min-Max) | 38.0 (18-59) | 59.0 (20-69) |
| Diagnoses | ||
| AML | 14 (43.8) | 25 (54.3) |
| CR1 | 8 | 13 |
| CR2 | 6 | 11 |
| ALL | 9 (28.1) | 3 (6.5) |
| CR1 | 7 | 1 |
| CR2 | 2 | 2 |
| CML | 1 (3.1) | 0 (0.0) |
| MDS | 3 (9.3) | 2 (4.3) |
| NHL | 3 (9.3) | 7 (15.2) |
| CR1 | 0 | 1 |
| CR2 | 1 | 1 |
| >CR2 | 2 | 5 |
| HL | 0 | 4 (8.7) |
| CR1 | — | 0 |
| CR2 | — | 2 |
| >CR2 | — | 2 |
| MPD/MM/other | 2 (6.2) | 5 (10.9) |
| DRI | ||
| Low | 4 (12.5) | 11 (24.4) |
| Intermediate | 24 (75) | 26 (57.8) |
| High | 4 (12.5) | 8 (17.8) |
| HCT-CI | ||
| <3 | 32(100) | 36 (78.3) |
| ≥3 | 0(0) | 10(21.7) |
| Karnofsky performance status (%) | ||
| ≥90 | 83.4 | 60.8 |
| <90 | 17.6 | 39.2 |
| Previous auto HSCT | 3 (9.4) | 6 (13) |
| CMV serology | ||
| Positive | 25 (78.1) | 39 (84.8) |
| Negative | 7 (21.9) | 7 (15.2) |
| Donor age (med) (y) (min-max) | 28.5 (14-65) | 34.5 (21-68) |
| Donor relation | ||
| Offspring | 7 | 27 |
| Sibling | 22 | 17 |
| Parent | 3 | 1 |
ALL, acute lymphoblastic leukemia; Max; maximum; MDS, myelodysplastic syndrome; Min, minimum; MM; med, median; MPD, myeloproliferative disease.