Table 3.

AE summary in all exposed patients

N (%) of patients with ≥1 AEN = 88
Any AE 84 (95.5) 
Most common AEs (≥20%)  
Neutropenia  24 (27.3) 
CRS  23 (26.1) 
Fatigue 23 (26.1) 
Rash 19 (21.6) 
Any mosunetuzumab-related AE 69 (78.4) 
Any grade 3 to 4 AE 51 (58.0) 
Most common grade 3 to 4 AEs (≥5%)  
Neutropenia  19 (21.6) 
Hypophosphatemia 10 (11.4) 
Anemia 8 (9.1) 
Febrile neutropenia 5 (5.7) 
Any mosunetuzumab-related grade 3 to 4 AE 37 (42.0) 
Any grade 5 AEs (not including PD)  3 (3.4) 
Any mosunetuzumab-related grade 5 AE 1 (1.1) 
Any AE leading to discontinuation of mosunetuzumab 4 (4.5) 
Any mosunetuzumab-related AE leading to discontinuation of mosunetuzumab 2 (2.3) 
Any AE leading to mosunetuzumab dose modification 1 (1.1) 
Any AE leading to mosunetuzumab dose interruption 22 (25.0) 
N (%) of patients with ≥1 AEN = 88
Any AE 84 (95.5) 
Most common AEs (≥20%)  
Neutropenia  24 (27.3) 
CRS  23 (26.1) 
Fatigue 23 (26.1) 
Rash 19 (21.6) 
Any mosunetuzumab-related AE 69 (78.4) 
Any grade 3 to 4 AE 51 (58.0) 
Most common grade 3 to 4 AEs (≥5%)  
Neutropenia  19 (21.6) 
Hypophosphatemia 10 (11.4) 
Anemia 8 (9.1) 
Febrile neutropenia 5 (5.7) 
Any mosunetuzumab-related grade 3 to 4 AE 37 (42.0) 
Any grade 5 AEs (not including PD)  3 (3.4) 
Any mosunetuzumab-related grade 5 AE 1 (1.1) 
Any AE leading to discontinuation of mosunetuzumab 4 (4.5) 
Any mosunetuzumab-related AE leading to discontinuation of mosunetuzumab 2 (2.3) 
Any AE leading to mosunetuzumab dose modification 1 (1.1) 
Any AE leading to mosunetuzumab dose interruption 22 (25.0) 

PD, progression of disease.

Includes events with term reported as neutropenia or neutrophil count decrease.

According to ASTCT 2019 grade.23 

Pneumonia, sepsis and cholangitis (1 patient each).

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