Multivariable Analysis of pre-ASCT variables for PFS
PFS . | |||||
---|---|---|---|---|---|
. | Term . | Univariable HR . | Univariable P value . | Multivariable HR . | Multivariable P value . |
ASC MRD-positive | |||||
Yes | 2.87 | <.001 | 3.73 | <.001 | |
Male | |||||
Male | 1.19 | .44 | |||
Age (60+) | |||||
Yes | 1.57 | .04 | 1.30 | .41 | |
Diagnosis | |||||
PMBCL | 0.62 | .41 | |||
TIL | 1.68 | .03 | |||
Primary refractory | |||||
Yes | 0.76 | .25 | |||
Chemo lines | |||||
3-4 | 1.43 | .17 | |||
Pre-ASCT CMR | |||||
Yes | 0.75 | .19 | |||
Pre-ASCT DS of 1-3∗ | |||||
Yes | 0.85 | .67 | |||
Conditioning | |||||
CBV | 1.16 | .52 | |||
Other | 1.10 | .89 | |||
DHL | |||||
Yes | 1.75 | .09 | 3.51 | .01 | |
DEL | |||||
Yes | 2.10 | .002 | 3.07 | <.001 |
PFS . | |||||
---|---|---|---|---|---|
. | Term . | Univariable HR . | Univariable P value . | Multivariable HR . | Multivariable P value . |
ASC MRD-positive | |||||
Yes | 2.87 | <.001 | 3.73 | <.001 | |
Male | |||||
Male | 1.19 | .44 | |||
Age (60+) | |||||
Yes | 1.57 | .04 | 1.30 | .41 | |
Diagnosis | |||||
PMBCL | 0.62 | .41 | |||
TIL | 1.68 | .03 | |||
Primary refractory | |||||
Yes | 0.76 | .25 | |||
Chemo lines | |||||
3-4 | 1.43 | .17 | |||
Pre-ASCT CMR | |||||
Yes | 0.75 | .19 | |||
Pre-ASCT DS of 1-3∗ | |||||
Yes | 0.85 | .67 | |||
Conditioning | |||||
CBV | 1.16 | .52 | |||
Other | 1.10 | .89 | |||
DHL | |||||
Yes | 1.75 | .09 | 3.51 | .01 | |
DEL | |||||
Yes | 2.10 | .002 | 3.07 | <.001 |
A subset of patients (53/98) had PET imaging available for retrospective assessment using the Deauville scoring system.