Table 2. Laboratory parameters of 16... | American Society of Hematology

Table 2.

Laboratory parameters of 16 well-documented acute iTTP episodes in 10 patients

Laboratory parameters at onset of the acute iTTP episode
Pat.ID	Sex	Severity of the acute episode (clinical score)∗	Platelets [cells/nL] 150-360	Hemoglobin [g/dL] m 13.5-17.5 f 12.0-16.0	Schistocytes [%] <5%	Haptoglobin [g/L] m 0.14-2.68 f 0.11-2.73	LDH [U/L] <245	VWF antigen [%] 42-176	VWF activity [%] 40-170	VWF MM ratio 1.1-3.5	ADAMTS13 activity [%] >50	ADAMTS13 antigen [μg/mL] >0.5	ADAMST13 CI <0.5	ADAMTS13 inhibitor [BU/mL] <0.5	IL-6 [pg/mL] <7	TNI [pg/mL] <24
11	F	Moderate (2)	97	11.1	10	0.09	307	242	336	3.1	1.4	0.24	7.57	0.3	<2	2.6
11	F	Moderate (2)	54	7.2	17	<0.08	609	216	373	3.1	2.6	0.25	0.48	0.8	3	252.6
11	F	Moderate (2)	65	9	5	0.82	444	228	>390	2.6	5.7	0.22	0.49	0	3	85.9
15	F	Laboratory abnormalities only (0)	17	11.7	3	<0.08	506	214	199	2.6	<1.0	0.07	8.49	1.0	3.53	<1.95
32	M	Moderate (2)	20	10.8	15	<0.08	527	226	215	2.2	<1.0	0.60	1.06	0.6	2	1.8
32	M	Moderate (2)	60	12.2	4	<0.08	505	227	283	3.2	<1.0	0.09	13.45	1.3	<2	9.4
44	M	Moderate (2)	88	9.9	14	<0.08	612	216	159	3.1	<1.0	0.20	3.9	2.6	3	133.6
45	F	Mild (1)	30	9.6	17	<0.08	413	106	70	0.7	1.6	0.08	0.33	0.9	<2	15.7
45	F	Moderate (2)	11	10.3	20	<0.08	697	162	130	0.9	<1.0	0.08	0.39	2.6	3	4.4
63	F	Mild (1)	29	10.4	17	<0.08	488	68	43	0.4	<1.0	0.06	9.56	0.7	3	1.8
63	F	Mild (1)	39	11.0	4	<0.08	297	78	69	2.8	4.8	0.17	5.13	1.4	<2	1.6
64	F	Mild (1)	49	10.2	11	<0.08	560	243	235	1.8	2.2	0.11	4.32	0.6	44	53.9
79	F	Moderate (2)	17	7.4	38	not done	749	177	149	0.5	<1.0	0.37	1.51	1.8	9	180.6
79	F	Mild (1)	11	7.8	31	<0.08	634	99	74	1.4	1.3	0.08	1.36	1.7	3	13.9
85	F	Severe (3)	6	6.9	23	<0.08	1678	261	not done	1.1	<1.0	0.05	4.03	1.2	14	2236.3
86	M	Severe (3)	8	10.1	15	<0.08	1165	230	122	0.6	<1.0	0.03	3.95	2.6	24	13.2

Laboratory parameters at onset of the acute iTTP episode
Pat.ID	Sex	Severity of the acute episode (clinical score)∗	Platelets [cells/nL] 150-360	Hemoglobin [g/dL] m 13.5-17.5 f 12.0-16.0	Schistocytes [%] <5%	Haptoglobin [g/L] m 0.14-2.68 f 0.11-2.73	LDH [U/L] <245	VWF antigen [%] 42-176	VWF activity [%] 40-170	VWF MM ratio 1.1-3.5	ADAMTS13 activity [%] >50	ADAMTS13 antigen [μg/mL] >0.5	ADAMST13 CI <0.5	ADAMTS13 inhibitor [BU/mL] <0.5	IL-6 [pg/mL] <7	TNI [pg/mL] <24
11	F	Moderate (2)	97	11.1	10	0.09	307	242	336	3.1	1.4	0.24	7.57	0.3	<2	2.6
11	F	Moderate (2)	54	7.2	17	<0.08	609	216	373	3.1	2.6	0.25	0.48	0.8	3	252.6
11	F	Moderate (2)	65	9	5	0.82	444	228	>390	2.6	5.7	0.22	0.49	0	3	85.9
15	F	Laboratory abnormalities only (0)	17	11.7	3	<0.08	506	214	199	2.6	<1.0	0.07	8.49	1.0	3.53	<1.95
32	M	Moderate (2)	20	10.8	15	<0.08	527	226	215	2.2	<1.0	0.60	1.06	0.6	2	1.8
32	M	Moderate (2)	60	12.2	4	<0.08	505	227	283	3.2	<1.0	0.09	13.45	1.3	<2	9.4
44	M	Moderate (2)	88	9.9	14	<0.08	612	216	159	3.1	<1.0	0.20	3.9	2.6	3	133.6
45	F	Mild (1)	30	9.6	17	<0.08	413	106	70	0.7	1.6	0.08	0.33	0.9	<2	15.7
45	F	Moderate (2)	11	10.3	20	<0.08	697	162	130	0.9	<1.0	0.08	0.39	2.6	3	4.4
63	F	Mild (1)	29	10.4	17	<0.08	488	68	43	0.4	<1.0	0.06	9.56	0.7	3	1.8
63	F	Mild (1)	39	11.0	4	<0.08	297	78	69	2.8	4.8	0.17	5.13	1.4	<2	1.6
64	F	Mild (1)	49	10.2	11	<0.08	560	243	235	1.8	2.2	0.11	4.32	0.6	44	53.9
79	F	Moderate (2)	17	7.4	38	not done	749	177	149	0.5	<1.0	0.37	1.51	1.8	9	180.6
79	F	Mild (1)	11	7.8	31	<0.08	634	99	74	1.4	1.3	0.08	1.36	1.7	3	13.9
85	F	Severe (3)	6	6.9	23	<0.08	1678	261	not done	1.1	<1.0	0.05	4.03	1.2	14	2236.3
86	M	Severe (3)	8	10.1	15	<0.08	1165	230	122	0.6	<1.0	0.03	3.95	2.6	24	13.2

BU, Bethesda Units; F, female; LDH, lactate dehydrogenase; M, male; Pat.ID, patient identification; TNI, troponin I.

Clinical severity score for acute iTTP episodes.⁴⁸