Univariate and multivariate Cox PH regression for OS in the training cohort (n = 211)
| . | . | 5 years OS % (95% CI) . | Univariate . | Multivariate . | ||
|---|---|---|---|---|---|---|
| Overall . | ||||||
| Factor . | Status . | . | HR (95% CI) . | P value . | HR (95% CI) . | P value . |
| Age, y | <60 | 61 (39-83) | 1.00 | .001 | 1.00 | .01 |
| >60 | 23 (14-32) | 1.6 (1.3-2.1) | 1.55 (1.3-2.1) | |||
| Albumin, g/L | >35 | 56 (32-80) | 1.00 | .003 | 1.00 | .004 |
| <35 | 25 (20-30) | 2.7 (1.8-4.2) | 2.13 (1.2-3.5) | |||
| LDH > ULN | <ULN | 58 (41-75) | 1.00 | .001 | 1.00 | .001 |
| >ULN | 28 (19-37) | 2.3 (1.4-3.4) | 2.02 (1.1-3.2) | |||
| Sex | Female | 45 (39-51) | 1.00 | .91 | ||
| Male | 45 (39-51) | 1.01 (0.7-1.5) | ||||
| B symptoms | No | 68 (42-94) | 1.00 | .001 | ||
| Yes | 27 (24-30) | 2.1 (1.3-3.1) | ||||
| ECOG PS | 0-1 | 51 (35-67) | 1.00 | .001 | ||
| 2-4 | 20 (14-26) | 2.7 (1.7-4.5) | ||||
| Extranodal involvement | No | 49 (36-62) | 1.00 | .82 | ||
| Yes | 46 (30-62) | 0.71 (0.6-1.4) | ||||
| Hb, g/L | >120 | 57 (36-78) | 1.00 | .001 | ||
| <120 | 29 (19-39) | 2.2 (1.5-3.3) | ||||
| Platelet count, ×109/L | >150 | 50 (31-69) | 1.00 | .02 | ||
| <150 | 29 (20-38) | 1.8 (1.1-3.7) | ||||
| . | . | 5 years OS % (95% CI) . | Univariate . | Multivariate . | ||
|---|---|---|---|---|---|---|
| Overall . | ||||||
| Factor . | Status . | . | HR (95% CI) . | P value . | HR (95% CI) . | P value . |
| Age, y | <60 | 61 (39-83) | 1.00 | .001 | 1.00 | .01 |
| >60 | 23 (14-32) | 1.6 (1.3-2.1) | 1.55 (1.3-2.1) | |||
| Albumin, g/L | >35 | 56 (32-80) | 1.00 | .003 | 1.00 | .004 |
| <35 | 25 (20-30) | 2.7 (1.8-4.2) | 2.13 (1.2-3.5) | |||
| LDH > ULN | <ULN | 58 (41-75) | 1.00 | .001 | 1.00 | .001 |
| >ULN | 28 (19-37) | 2.3 (1.4-3.4) | 2.02 (1.1-3.2) | |||
| Sex | Female | 45 (39-51) | 1.00 | .91 | ||
| Male | 45 (39-51) | 1.01 (0.7-1.5) | ||||
| B symptoms | No | 68 (42-94) | 1.00 | .001 | ||
| Yes | 27 (24-30) | 2.1 (1.3-3.1) | ||||
| ECOG PS | 0-1 | 51 (35-67) | 1.00 | .001 | ||
| 2-4 | 20 (14-26) | 2.7 (1.7-4.5) | ||||
| Extranodal involvement | No | 49 (36-62) | 1.00 | .82 | ||
| Yes | 46 (30-62) | 0.71 (0.6-1.4) | ||||
| Hb, g/L | >120 | 57 (36-78) | 1.00 | .001 | ||
| <120 | 29 (19-39) | 2.2 (1.5-3.3) | ||||
| Platelet count, ×109/L | >150 | 50 (31-69) | 1.00 | .02 | ||
| <150 | 29 (20-38) | 1.8 (1.1-3.7) | ||||
HR, hazard ratio; ULN, upper limit of normal.