Summary of overall response per the IWG 2007 criteria by investigator assessment in patients who received second-course treatment and had response data at data cutoff
| . | Cohort 1 (n = 9) . | Cohort 2 (n = 7) . | Cohort 3 (n = 3) . | Total (n = 19) . |
|---|---|---|---|---|
| ORR, % (95% CI) | 77.8 (40.0-97.2) | 85.7 (42.1-99.6) | 33.3 (0.8-90.6) | 73.7 (48.8-90.8) |
| BOR, n (%) | ||||
| CR | 1 (11.1) | 6 (85.7) | 0 (0) | 7 (36.8) |
| PR | 6 (66.7) | 0 (0) | 1 (33.3) | 7 (36.8) |
| SD | 1 (11.1) | 0 (0) | 2 (66.7) | 3 (15.8) |
| PD | 1 (11.1) | 1 (14.3) | 0 (0) | 2 (10.5) |
| . | Cohort 1 (n = 9) . | Cohort 2 (n = 7) . | Cohort 3 (n = 3) . | Total (n = 19) . |
|---|---|---|---|---|
| ORR, % (95% CI) | 77.8 (40.0-97.2) | 85.7 (42.1-99.6) | 33.3 (0.8-90.6) | 73.7 (48.8-90.8) |
| BOR, n (%) | ||||
| CR | 1 (11.1) | 6 (85.7) | 0 (0) | 7 (36.8) |
| PR | 6 (66.7) | 0 (0) | 1 (33.3) | 7 (36.8) |
| SD | 1 (11.1) | 0 (0) | 2 (66.7) | 3 (15.8) |
| PD | 1 (11.1) | 1 (14.3) | 0 (0) | 2 (10.5) |
One patient was not included because response data were not available at the time of data cutoff.
BOR, best overall response; SD, stable disease.