Univariate and multivariate Cox regression for OS and RFS by insurance status and COI
| . | OS (n = 206)∗ . | RFS (n = 192)† . | ||||||
|---|---|---|---|---|---|---|---|---|
| Unadjusted HR (95% CI) . | P . | Adjusted HR (95% CI) . | P . | Unadjusted HR (95% CI) . | P . | Adjusted HR (95% CI) . | P . | |
| Insurance‡ | ||||||||
| Commercial | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
| Medicaid | 0.8 (0.5-1.4) | 0.484 | 1.0 (0.5-2.0) | 0.971 | 0.8(0.5-1.3) | 0.452 | 0.7 (0.4-1.3) | 0.273 |
| COI§ | ||||||||
| High | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
| Low | 0.9 (0.5-1.7) | 0.724 | 1.2 (0.6-2.4) | 0.545 | 1.5 (0.9-2.4) | 0.104 | 2.3 (1.3-4.1) | 0.006 |
| COI health/environment|| | ||||||||
| High | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
| Low | 1.1 (0.6-1.9) | 0.780 | 1.1 (0.6-2.0) | 0.851 | 1.1 (0.7-1.9) | 0.658 | 1.4 (0.8-2.5) | 0.296 |
| COI education¶ | ||||||||
| High | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
| Low | 1.0 (0.6-1.8) | 0.997 | 1.2 (0.6-2.3) | 0.636 | 1.2 (0.7-2.0) | 0.445 | 1.6 (0.9-3.0) | 0.107 |
| COI social/economic§ | ||||||||
| High | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
| Low | 0.7 (0.4-1.3) | 0.277 | 0.8 (0.4-1.7) | 0.626 | 1.3 (0.8-2.2) | 0.276 | 1.6 (0.9-2.8) | 0.105 |
| . | OS (n = 206)∗ . | RFS (n = 192)† . | ||||||
|---|---|---|---|---|---|---|---|---|
| Unadjusted HR (95% CI) . | P . | Adjusted HR (95% CI) . | P . | Unadjusted HR (95% CI) . | P . | Adjusted HR (95% CI) . | P . | |
| Insurance‡ | ||||||||
| Commercial | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
| Medicaid | 0.8 (0.5-1.4) | 0.484 | 1.0 (0.5-2.0) | 0.971 | 0.8(0.5-1.3) | 0.452 | 0.7 (0.4-1.3) | 0.273 |
| COI§ | ||||||||
| High | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
| Low | 0.9 (0.5-1.7) | 0.724 | 1.2 (0.6-2.4) | 0.545 | 1.5 (0.9-2.4) | 0.104 | 2.3 (1.3-4.1) | 0.006 |
| COI health/environment|| | ||||||||
| High | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
| Low | 1.1 (0.6-1.9) | 0.780 | 1.1 (0.6-2.0) | 0.851 | 1.1 (0.7-1.9) | 0.658 | 1.4 (0.8-2.5) | 0.296 |
| COI education¶ | ||||||||
| High | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
| Low | 1.0 (0.6-1.8) | 0.997 | 1.2 (0.6-2.3) | 0.636 | 1.2 (0.7-2.0) | 0.445 | 1.6 (0.9-3.0) | 0.107 |
| COI social/economic§ | ||||||||
| High | Ref | Ref | Ref | Ref | Ref | Ref | Ref | Ref |
| Low | 0.7 (0.4-1.3) | 0.277 | 0.8 (0.4-1.7) | 0.626 | 1.3 (0.8-2.2) | 0.276 | 1.6 (0.9-2.8) | 0.105 |
Ref, reference.
COI analyses include 201 patients, removing patients missing COI.
COI analyses include 188 patients, removing patients missing COI and not in CR.
Multivariate model adjusted for: age, race and ethnicity, disease status, prior inotuzumab, product, disease burden.
Multivariate model adjusted for: age, race and ethnicity, disease burden.
Multivariate model adjusted for: age, race and ethnicity, disease status, cytogenetics, disease burden.
Multivariate model adjusted for: age, sex, race and ethnicity, relapse status, cytogenetics, disease burden.