Table 2.

Secondary efficacy end points

Outcome measureRivipansel (N = 173)Placebo (N = 172)P valueHazard ratio
Time to discharge, median (95% CI), h 86.8 (71.3-98.7) 90.7 (72.1-108.6) .72 0.96 
Cumulative IV opioid use, median, morphine-equivalent units/kg 2.30 2.36 .85  [Ratio of medians = 1.01] 
Time to discontinuation of IV opioids, median (95% CI), h 67.2 (53.3-80.5) 68.5 (53.8-85.0) .86 1.02 
Outcome measureRivipansel (N = 173)Placebo (N = 172)P valueHazard ratio
Time to discharge, median (95% CI), h 86.8 (71.3-98.7) 90.7 (72.1-108.6) .72 0.96 
Cumulative IV opioid use, median, morphine-equivalent units/kg 2.30 2.36 .85  [Ratio of medians = 1.01] 
Time to discontinuation of IV opioids, median (95% CI), h 67.2 (53.3-80.5) 68.5 (53.8-85.0) .86 1.02 

Based on a rank analysis of covariance model.

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