Comparisons of IEI-related complications in transplanted and matched nontransplanted patients with CGD
Complications at baseline . | All patients (n = 69) . | No alloSCT (n = 49) . | alloSCT (n = 20) . | P value . |
---|---|---|---|---|
Infections | ||||
Bacterial infection | 56 (81%) | 37 (76%) | 19 (95%) | .09 |
Viral infection | 1 (1%) | 1 (2%) | 0 (0%) | 1 |
Fungal infection | 33 (48%) | 22 (45%) | 11 (55%) | .446 |
Invasive aspergillosis | 28 (41%) | 19 (39%) | 9 (45%) | .633 |
Autoimmune cytopenia | 1 (1%) | 1 (2%) | 0 | 1 |
Colitis | 29 (42%) | 19 (39%) | 10 (50%) | .391 |
Granuloma | 20 (29%) | 14 (29%) | 6 (30%) | .906 |
Liver involvement∗ | 4 (6%) | 4 (8%) | 0 (0%) | .315 |
Interstitial pulmonary involvement | 8 (12%) | 7 (14%) | 1 (5%) | .422 |
Hemophagocytic syndrome | 1 (1%) | 1 (2%) | 0 | 1 |
Lymphoid proliferation | 1 (1%) | 1 (2%) | 0 | 1 |
Complications at baseline . | All patients (n = 69) . | No alloSCT (n = 49) . | alloSCT (n = 20) . | P value . |
---|---|---|---|---|
Infections | ||||
Bacterial infection | 56 (81%) | 37 (76%) | 19 (95%) | .09 |
Viral infection | 1 (1%) | 1 (2%) | 0 (0%) | 1 |
Fungal infection | 33 (48%) | 22 (45%) | 11 (55%) | .446 |
Invasive aspergillosis | 28 (41%) | 19 (39%) | 9 (45%) | .633 |
Autoimmune cytopenia | 1 (1%) | 1 (2%) | 0 | 1 |
Colitis | 29 (42%) | 19 (39%) | 10 (50%) | .391 |
Granuloma | 20 (29%) | 14 (29%) | 6 (30%) | .906 |
Liver involvement∗ | 4 (6%) | 4 (8%) | 0 (0%) | .315 |
Interstitial pulmonary involvement | 8 (12%) | 7 (14%) | 1 (5%) | .422 |
Hemophagocytic syndrome | 1 (1%) | 1 (2%) | 0 | 1 |
Lymphoid proliferation | 1 (1%) | 1 (2%) | 0 | 1 |
Liver involvement included hepatic fibrosis in 2 patients and granulomatous hepatitis in 2 patients.