Table 2.

Comparisons of IEI-related complications in transplanted and matched nontransplanted patients with CGD

Complications at baselineAll patients (n = 69)No alloSCT (n = 49)alloSCT (n = 20)P value
Infections     
Bacterial infection 56 (81%) 37 (76%) 19 (95%) .09 
Viral infection 1 (1%) 1 (2%) 0 (0%) 
Fungal infection 33 (48%) 22 (45%) 11 (55%) .446 
Invasive aspergillosis 28 (41%) 19 (39%) 9 (45%) .633 
Autoimmune cytopenia 1 (1%) 1 (2%) 
Colitis 29 (42%) 19 (39%) 10 (50%) .391 
Granuloma 20 (29%) 14 (29%) 6 (30%) .906 
Liver involvement  4 (6%) 4 (8%) 0 (0%) .315 
Interstitial pulmonary involvement 8 (12%) 7 (14%) 1 (5%) .422 
Hemophagocytic syndrome 1 (1%) 1 (2%) 
Lymphoid proliferation 1 (1%) 1 (2%) 
Complications at baselineAll patients (n = 69)No alloSCT (n = 49)alloSCT (n = 20)P value
Infections     
Bacterial infection 56 (81%) 37 (76%) 19 (95%) .09 
Viral infection 1 (1%) 1 (2%) 0 (0%) 
Fungal infection 33 (48%) 22 (45%) 11 (55%) .446 
Invasive aspergillosis 28 (41%) 19 (39%) 9 (45%) .633 
Autoimmune cytopenia 1 (1%) 1 (2%) 
Colitis 29 (42%) 19 (39%) 10 (50%) .391 
Granuloma 20 (29%) 14 (29%) 6 (30%) .906 
Liver involvement  4 (6%) 4 (8%) 0 (0%) .315 
Interstitial pulmonary involvement 8 (12%) 7 (14%) 1 (5%) .422 
Hemophagocytic syndrome 1 (1%) 1 (2%) 
Lymphoid proliferation 1 (1%) 1 (2%) 

Liver involvement included hepatic fibrosis in 2 patients and granulomatous hepatitis in 2 patients.

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