Multivariable analysis of the association of cardiac events with OS and PFS
| . | Model 1 . | Model 2 . | ||||
|---|---|---|---|---|---|---|
| N (event N) . | HR (95% CI) . | P value . | N (event N) . | HR (95% CI) . | P value . | |
| OS | ||||||
| Cardiac event | ||||||
| No | 67 (11) | 1.00 (referent) | .20 | 65 (11) | 1.00 (referent) | .09 |
| Yes | 11 (5) | 2.07 (0.71-6.06) | 11 (5) | 2.66 (0.85-8.26) | ||
| PFS | ||||||
| Cardiac event | ||||||
| No | 67 (31) | 1.00 (referent) | .30 | 65 (30) | 1.00 (referent) | .09 |
| Yes | 11 (9) | 1.52 (0.71-3.22) | 11 (9) | 1.98 (0.90-4.37) | ||
| . | Model 1 . | Model 2 . | ||||
|---|---|---|---|---|---|---|
| N (event N) . | HR (95% CI) . | P value . | N (event N) . | HR (95% CI) . | P value . | |
| OS | ||||||
| Cardiac event | ||||||
| No | 67 (11) | 1.00 (referent) | .20 | 65 (11) | 1.00 (referent) | .09 |
| Yes | 11 (5) | 2.07 (0.71-6.06) | 11 (5) | 2.66 (0.85-8.26) | ||
| PFS | ||||||
| Cardiac event | ||||||
| No | 67 (31) | 1.00 (referent) | .30 | 65 (30) | 1.00 (referent) | .09 |
| Yes | 11 (9) | 1.52 (0.71-3.22) | 11 (9) | 1.98 (0.90-4.37) | ||
Model 1 is unadjusted.
Model 2 is adjusted for age at CAR-T infusion, prior BCMA therapy, and high-risk cytogenetics.
HR, hazard ratio.