Adverse events
| Toxicity . | All grades . | Grade 3-4 . |
|---|---|---|
| Treatment emergent, n (%) | ||
| Abdominal pain | 2 (17) | 0 (0) |
| Abnormal LFTs | 3 (25) | 0 (0) |
| Anorexia | 3 (25) | 0 (0) |
| Arthralgias | 3 (25) | 0 (0) |
| Chest pain | 1 (8) | 0 (0) |
| Clostridiumdifficile infection | 1 (8) | 0 (0) |
| Constipation | 1 (8) | 0 (0) |
| Cough | 1 (8) | 0 (0) |
| Cramps | 1 (8) | 0 (0) |
| Epistaxis | 1 (8) | 0 (0) |
| Fatigue | 7 (58) | 1 (8) |
| Fever | 4 (33) | 2 (17) |
| Headache | 2 (17) | 0 (0) |
| Hyperkalemia | 1 (8) | 0 (0) |
| Infusion reaction | 1 (8) | 0 (0) |
| Nausea or vomiting | 4 (33) | 0 (0) |
| Pain | 1 (8) | 0 (0) |
| Pneumonia | 1 (8) | 1 (8) |
| Rash | 2 (17) | 0 (0) |
| Secondary malignancy | 1 (8) | 1 (8) |
| URI | 2 (17) | 0 (0) |
| UTI | 1 (8) | 0 (0) |
| Toxicity . | All grades . | Grade 3-4 . |
|---|---|---|
| Treatment emergent, n (%) | ||
| Abdominal pain | 2 (17) | 0 (0) |
| Abnormal LFTs | 3 (25) | 0 (0) |
| Anorexia | 3 (25) | 0 (0) |
| Arthralgias | 3 (25) | 0 (0) |
| Chest pain | 1 (8) | 0 (0) |
| Clostridiumdifficile infection | 1 (8) | 0 (0) |
| Constipation | 1 (8) | 0 (0) |
| Cough | 1 (8) | 0 (0) |
| Cramps | 1 (8) | 0 (0) |
| Epistaxis | 1 (8) | 0 (0) |
| Fatigue | 7 (58) | 1 (8) |
| Fever | 4 (33) | 2 (17) |
| Headache | 2 (17) | 0 (0) |
| Hyperkalemia | 1 (8) | 0 (0) |
| Infusion reaction | 1 (8) | 0 (0) |
| Nausea or vomiting | 4 (33) | 0 (0) |
| Pain | 1 (8) | 0 (0) |
| Pneumonia | 1 (8) | 1 (8) |
| Rash | 2 (17) | 0 (0) |
| Secondary malignancy | 1 (8) | 1 (8) |
| URI | 2 (17) | 0 (0) |
| UTI | 1 (8) | 0 (0) |
| Toxicity . | All grades . | Grade 3-4 . |
|---|---|---|
| irAE, n (%) | ||
| Hemolytic anemia | 1 (8) | 1 (8) |
| Elevated LFTs | 1 (8) | 0 (0) |
| Hyperthyroidism | 1 (8) | 1 (8) |
| ITP | 1 (8) | 1 (8) |
| Pneumonitis | 2 (17) | 2 (17) |
| Rash | 3 (25) | 0 (0) |
| Toxicity . | All grades . | Grade 3-4 . |
|---|---|---|
| irAE, n (%) | ||
| Hemolytic anemia | 1 (8) | 1 (8) |
| Elevated LFTs | 1 (8) | 0 (0) |
| Hyperthyroidism | 1 (8) | 1 (8) |
| ITP | 1 (8) | 1 (8) |
| Pneumonitis | 2 (17) | 2 (17) |
| Rash | 3 (25) | 0 (0) |
ITP, idiopathic thrombocytopenic purpura; LFT, liver function test; URI, upper respiratory infection; UTI, urinary tract infection.