Four-month hematological response to first-line treatment depending on the severity of AA
| . | SAA (ANC ≥0.2 × 109/L) (n = 39) . | vSAA (ANC <0.2 × 109/L) (n = 59) . | ||||||
|---|---|---|---|---|---|---|---|---|
| ELTR + IST (n = 18), n (%) . | IST (n = 21), n (%) . | Difference in % (95% CI) . | P value . | ELTR + IST (n = 31), n (%) . | IST (n = 28), n (%) . | Difference in % (95% CI) . | P value . | |
| OR | 16 (89) | 12 (57) | 32 (6 to 57) | .028 | 16 (52) | 14 (50) | 2 (−24 to 27) | .902 |
| CR | 8 (44) | 6 (29) | 16 (−14 to 46) | .303 | 7 (23) | 0 (0) | 23 (8 to 37) | .011 |
| PR | 8 (44) | 6 (29) | — | — | 9 (29) | 14 (50) | — | — |
| NR | 2 (11) | 9 (43) | −32 (−57 to −6) | .028 | 14 (45) | 14 (50) | −5 (−30 to 21) | .710 |
| Death | 0 (0) | 0 (0) | — | — | 1 (3) | 0 (0) | — | — |
| . | SAA (ANC ≥0.2 × 109/L) (n = 39) . | vSAA (ANC <0.2 × 109/L) (n = 59) . | ||||||
|---|---|---|---|---|---|---|---|---|
| ELTR + IST (n = 18), n (%) . | IST (n = 21), n (%) . | Difference in % (95% CI) . | P value . | ELTR + IST (n = 31), n (%) . | IST (n = 28), n (%) . | Difference in % (95% CI) . | P value . | |
| OR | 16 (89) | 12 (57) | 32 (6 to 57) | .028 | 16 (52) | 14 (50) | 2 (−24 to 27) | .902 |
| CR | 8 (44) | 6 (29) | 16 (−14 to 46) | .303 | 7 (23) | 0 (0) | 23 (8 to 37) | .011 |
| PR | 8 (44) | 6 (29) | — | — | 9 (29) | 14 (50) | — | — |
| NR | 2 (11) | 9 (43) | −32 (−57 to −6) | .028 | 14 (45) | 14 (50) | −5 (−30 to 21) | .710 |
| Death | 0 (0) | 0 (0) | — | — | 1 (3) | 0 (0) | — | — |