Results of the Cox regression models
| Parameter . | Univariate analysis . | Multivariate analysis . | ||||
|---|---|---|---|---|---|---|
| Hazard ratio . | 95% CI . | P . | Hazard ratio . | 95% CI . | P . | |
| Age | 1.02 | 1.00-1.04 | .06 | 1.03 | 0.98-1.08 | .25 |
| Male sex | 1.89 | 0.81-4.40 | .14 | — | — | — |
| Malignancy | 3.40 | 1.61-7.19 | .001 | 1.92 | 0.43-8.64 | .39 |
| Albumin | 0.54 | 0.28-1.04 | .07 | 0.56 | 0.17-1.88 | .35 |
| AST∗ | 1.02 | 1.00-1.05 | .07 | 1.00 | 0.95-1.05 | .96 |
| Creatinine | 1.32 | 1.04-1.68 | .02 | 1.16 | 0.71-1.92 | .55 |
| Ferritin† | 1.01 | 0.91-1.11 | .93 | — | — | — |
| Fibrinogen | 1.00 | 1.00-1.00 | .24 | — | — | — |
| Hemoglobin | 0.93 | 0.77-1.13 | .48 | — | — | — |
| INR | 3.24 | 1.50-7.00 | .003 | 1.07 | 0.28-4.06 | .92 |
| LDH† | 1.15 | 1.02-1.29 | .02 | 1.27 | 0.95-1.70 | .11 |
| Leukocytes | 1.01 | 0.97-1.05 | .65 | — | — | — |
| Neutrophils | 1.02 | 0.97-1.07 | .55 | — | — | — |
| Platelets | 0.99 | 0.98-1.00 | .005 | 1.00 | 0.99-1.01 | .76 |
| sCD25‡ | 2.40 | 1.67-3.44 | <.0001 | 2.22 | 1.28-3.87 | .005 |
| Triglycerides | 1.00 | 1.00-1.00 | .78 | — | — | — |
| Parameter . | Univariate analysis . | Multivariate analysis . | ||||
|---|---|---|---|---|---|---|
| Hazard ratio . | 95% CI . | P . | Hazard ratio . | 95% CI . | P . | |
| Age | 1.02 | 1.00-1.04 | .06 | 1.03 | 0.98-1.08 | .25 |
| Male sex | 1.89 | 0.81-4.40 | .14 | — | — | — |
| Malignancy | 3.40 | 1.61-7.19 | .001 | 1.92 | 0.43-8.64 | .39 |
| Albumin | 0.54 | 0.28-1.04 | .07 | 0.56 | 0.17-1.88 | .35 |
| AST∗ | 1.02 | 1.00-1.05 | .07 | 1.00 | 0.95-1.05 | .96 |
| Creatinine | 1.32 | 1.04-1.68 | .02 | 1.16 | 0.71-1.92 | .55 |
| Ferritin† | 1.01 | 0.91-1.11 | .93 | — | — | — |
| Fibrinogen | 1.00 | 1.00-1.00 | .24 | — | — | — |
| Hemoglobin | 0.93 | 0.77-1.13 | .48 | — | — | — |
| INR | 3.24 | 1.50-7.00 | .003 | 1.07 | 0.28-4.06 | .92 |
| LDH† | 1.15 | 1.02-1.29 | .02 | 1.27 | 0.95-1.70 | .11 |
| Leukocytes | 1.01 | 0.97-1.05 | .65 | — | — | — |
| Neutrophils | 1.02 | 0.97-1.07 | .55 | — | — | — |
| Platelets | 0.99 | 0.98-1.00 | .005 | 1.00 | 0.99-1.01 | .76 |
| sCD25‡ | 2.40 | 1.67-3.44 | <.0001 | 2.22 | 1.28-3.87 | .005 |
| Triglycerides | 1.00 | 1.00-1.00 | .78 | — | — | — |
AST, aspartate transaminase; CI, confidence interval; INR, international normalized ratio; LDH, lactate dehydrogenase; sCD25, alpha chain of the soluble interleukin-2 receptor.
Absolute laboratory values divided by 100 before entering to the Cox regression model.
Absolute laboratory values divided by 1000 before entering to the Cox regression model.
Absolute laboratory values divided by 10 000 before entering to the Cox regression model.