Treatment-free response rates at 12 months in adults with ITP treated with medical therapy

StudyDuration of ITPInterventionDefinition of platelet responseResponse rate at 12 mo, %
Godeau et al6  <3 mo Methylprednisolone 15 mg/kg per d × 3 d >50 × 109 32 
Godeau et al6  <3 mo IVIG 0.7 g/kg per d × 3 d >50 × 109 29 
Gudbrandsdottir et al7  <3 mo Dexamethasone 40 mg/d × 4 d for up to 6 cycles ≥50 × 109 33 
Patel et al8  Mix of newly diagnosed, persistent, and chronic Rituximab 375 mg/m2 × 4 doses ≥50 × 109 38 
StudyDuration of ITPInterventionDefinition of platelet responseResponse rate at 12 mo, %
Godeau et al6  <3 mo Methylprednisolone 15 mg/kg per d × 3 d >50 × 109 32 
Godeau et al6  <3 mo IVIG 0.7 g/kg per d × 3 d >50 × 109 29 
Gudbrandsdottir et al7  <3 mo Dexamethasone 40 mg/d × 4 d for up to 6 cycles ≥50 × 109 33 
Patel et al8  Mix of newly diagnosed, persistent, and chronic Rituximab 375 mg/m2 × 4 doses ≥50 × 109 38 
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