Table 3.

Univariate factors associated with pre–CAR-T QOL

Variableβ (95% CI)Standard errorP value
Age (y) 0.54 (0.26-0.82) 0.14 < .001 
Female sex −1.48 (−8.61 to 5.65) 3.59 .682 
Married/with a partner 6.51(–1.80 to 14.8) 4.18 .123 
College educated 7.91 (1.06-14.7) 3.45 .024 
Income ≥ $100 000 7.94 (0.88-15.0) 3.55 .028 
White race 6.96 (−3.44 to 17.4) 5.24 .187 
Bridging therapy use −8.99 (–16.2 to –1.82) 3.61 .015 
ECOG performance status −9.91 (–15.4 to –4.46) 2.74 < .001 
Diagnosis of lymphoma/leukemia 3.80 (−3.78 to 11.4) 3.82 .322 
Months since diagnosis −0.04 (−0.11 to 0.03) 0.03 .236 
CAR-T product    
B-cell maturation antigen CAR-T (ref) Ref Ref Ref 
Tisa-cel 0.06 (−8.72 to 8.83) 4.42 .990 
Axi-cel or Brexu-cel 8.37 (−1.71 to 18.4) 5.07 .102 
Liso-cel 6.21 (−4.42 to 16.8) 5.35 .249 
Variableβ (95% CI)Standard errorP value
Age (y) 0.54 (0.26-0.82) 0.14 < .001 
Female sex −1.48 (−8.61 to 5.65) 3.59 .682 
Married/with a partner 6.51(–1.80 to 14.8) 4.18 .123 
College educated 7.91 (1.06-14.7) 3.45 .024 
Income ≥ $100 000 7.94 (0.88-15.0) 3.55 .028 
White race 6.96 (−3.44 to 17.4) 5.24 .187 
Bridging therapy use −8.99 (–16.2 to –1.82) 3.61 .015 
ECOG performance status −9.91 (–15.4 to –4.46) 2.74 < .001 
Diagnosis of lymphoma/leukemia 3.80 (−3.78 to 11.4) 3.82 .322 
Months since diagnosis −0.04 (−0.11 to 0.03) 0.03 .236 
CAR-T product    
B-cell maturation antigen CAR-T (ref) Ref Ref Ref 
Tisa-cel 0.06 (−8.72 to 8.83) 4.42 .990 
Axi-cel or Brexu-cel 8.37 (−1.71 to 18.4) 5.07 .102 
Liso-cel 6.21 (−4.42 to 16.8) 5.35 .249 

Ref., reference.

β-weights indicate differences in FACT-G QOL score based on each univariate predictor. Bolded values are for those with a P value < 0.05.

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