Multivariable adjustment for overall survival per current risk stratification
| Characteristic . | HR . | 95% CI . | P . |
|---|---|---|---|
| Model for survival | |||
| Concordance index: 0.71 | |||
| AIC: 979.11 | |||
| TP53status | |||
| WT | Reference | ||
| Single-hit | 1.44 | 0.69-3.01 | .33 |
| Multihit | 2.12 | 1.29-3.49 | .003 |
| MTSS | |||
| Low | Reference | ||
| Intermediate | 2.44 | 1.25-4.79 | .01 |
| High | 5.11 | 2.60-10.03 | <.001 |
| Very high | 7.53 | 3.85-14.74 | <.001 |
| Myeloablative conditioning | 1.35 | 0.88-2.09 | .17 |
| Model for relapse | |||
| Concordance index: 0.68 | |||
| AIC: 1252.43 | |||
| TP53status | |||
| WT | Reference | ||
| Single-hit | 0.85 | 0.26-2.81 | .79 |
| Multihit | 3.30 | 1.78-6.09 | <.001 |
| MTSS | |||
| Low | Reference | ||
| Intermediate | 1.25 | 0.64-2.44 | .51 |
| High | 1.55 | 0.76-3.18 | .23 |
| Very high | 2.26 | 1.10-4.67 | .03 |
| Myeloablative conditioning | 1.10 | 0.62-1.94 | .75 |
| Characteristic . | HR . | 95% CI . | P . |
|---|---|---|---|
| Model for survival | |||
| Concordance index: 0.71 | |||
| AIC: 979.11 | |||
| TP53status | |||
| WT | Reference | ||
| Single-hit | 1.44 | 0.69-3.01 | .33 |
| Multihit | 2.12 | 1.29-3.49 | .003 |
| MTSS | |||
| Low | Reference | ||
| Intermediate | 2.44 | 1.25-4.79 | .01 |
| High | 5.11 | 2.60-10.03 | <.001 |
| Very high | 7.53 | 3.85-14.74 | <.001 |
| Myeloablative conditioning | 1.35 | 0.88-2.09 | .17 |
| Model for relapse | |||
| Concordance index: 0.68 | |||
| AIC: 1252.43 | |||
| TP53status | |||
| WT | Reference | ||
| Single-hit | 0.85 | 0.26-2.81 | .79 |
| Multihit | 3.30 | 1.78-6.09 | <.001 |
| MTSS | |||
| Low | Reference | ||
| Intermediate | 1.25 | 0.64-2.44 | .51 |
| High | 1.55 | 0.76-3.18 | .23 |
| Very high | 2.26 | 1.10-4.67 | .03 |
| Myeloablative conditioning | 1.10 | 0.62-1.94 | .75 |
MTSS was in accordance with that given by Gagelmann et al.12
AIC, Akaike information criterion.