Table 1.

Clinical and biological features of infant patient with ALL on Total 16

CaseRisk statusAge (y)WBC (×109/L)SexRaceLineageSubtypeCNS statusDay 15 induction MRD End of induction MRD Outcome
High 0.71 31.1 White B cell KMT2A-MLLT10 CNS-3 1.38% Neg Alive CR1 
Standard 0.82 61.8 Other B cell ACIN-NUTM1 Traumatic no blasts Neg Neg Alive CR1 
High 0.16 54.4 White B cell KMT2A-AFF1 Traumatic with blasts Neg Neg Expired TRM 
High 0.82 32.9 White B cell KMT2A-MLLT10 Traumatic no blasts 13.7% Neg Alive CR1 
High 0.44 52 White B cell KMT2A-AFF1 Traumatic with blasts Neg Neg Alive CR1 
High 0.71 450 White B cell KMT2A-MLLT1 CNS-2 0.012% 0.07% Alive CR1 
Standard 0.79 11.2 White B cell Hyperdiploid 51+ CNS-3 0.006% Neg Alive CR1 
High 0.52 411.9 White B cell KMT2A-EPS15 Traumatic with blasts 1.274% Neg Expired TRM 
High 0.56 6.7 Other B cell KMT2A-MLLT1 CNS-2 Neg ND  Expired TRM 
10 High 0.12 905.3 White B cell KMT2A-MLLT1 Traumatic with blasts 2.911% 0.011% Expired TRM 
11 High 0.2 95.8 Other T cell γδ T cell Traumatic with blasts 31.73% 0.034% Expired Relapse 
12 High 0.18 125.3 White B cell KMT2A-AFF1 CNS-2 2.88% Neg Alive CR2 
CaseRisk statusAge (y)WBC (×109/L)SexRaceLineageSubtypeCNS statusDay 15 induction MRD End of induction MRD Outcome
High 0.71 31.1 White B cell KMT2A-MLLT10 CNS-3 1.38% Neg Alive CR1 
Standard 0.82 61.8 Other B cell ACIN-NUTM1 Traumatic no blasts Neg Neg Alive CR1 
High 0.16 54.4 White B cell KMT2A-AFF1 Traumatic with blasts Neg Neg Expired TRM 
High 0.82 32.9 White B cell KMT2A-MLLT10 Traumatic no blasts 13.7% Neg Alive CR1 
High 0.44 52 White B cell KMT2A-AFF1 Traumatic with blasts Neg Neg Alive CR1 
High 0.71 450 White B cell KMT2A-MLLT1 CNS-2 0.012% 0.07% Alive CR1 
Standard 0.79 11.2 White B cell Hyperdiploid 51+ CNS-3 0.006% Neg Alive CR1 
High 0.52 411.9 White B cell KMT2A-EPS15 Traumatic with blasts 1.274% Neg Expired TRM 
High 0.56 6.7 Other B cell KMT2A-MLLT1 CNS-2 Neg ND  Expired TRM 
10 High 0.12 905.3 White B cell KMT2A-MLLT1 Traumatic with blasts 2.911% 0.011% Expired TRM 
11 High 0.2 95.8 Other T cell γδ T cell Traumatic with blasts 31.73% 0.034% Expired Relapse 
12 High 0.18 125.3 White B cell KMT2A-AFF1 CNS-2 2.88% Neg Alive CR2 

WBC, white blood cell.

MRD, minimal residual disease as determined by flow cytometry.

ND, not determined, patient expired before CCE and did not have an end of induction marrow.

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