Transfusion characteristics of the patients
| . | Median (IQR) . | Mean (SD) . | P . |
|---|---|---|---|
| Overall (n = 135) | |||
| Transfusion volume before combination therapy | 950 (0-2100) | 1106.4 (1041.8) | <.001 |
| Transfusion volume after combination therapy | 0 (0-300) | 315.6 (616.7) | |
| Good responder (n = 89) | |||
| Transfusion volume before combination therapy | 900 (55-1750) | 991.6 (897.9) | <.001 |
| Transfusion volume after combination therapy | 0 (0-0) | 168.9 (484.7) | |
| Responders (n = 16) | |||
| Transfusion volume before combination therapy | 1575 (555-2362) | 1677.5 (1394.2) | .003 |
| Transfusion volume after combination therapy | 350 (0-975) | 618.7 (748.9) | |
| Nonresponders (n = 30) | |||
| Transfusion volume before combination therapy | 1050 (0-2100) | 1142.3 (1158.1) | .002 |
| Transfusion volume after combination therapy | 0 (0-1400) | 589 (748.5) | |
| . | Median (IQR) . | Mean (SD) . | P . |
|---|---|---|---|
| Overall (n = 135) | |||
| Transfusion volume before combination therapy | 950 (0-2100) | 1106.4 (1041.8) | <.001 |
| Transfusion volume after combination therapy | 0 (0-300) | 315.6 (616.7) | |
| Good responder (n = 89) | |||
| Transfusion volume before combination therapy | 900 (55-1750) | 991.6 (897.9) | <.001 |
| Transfusion volume after combination therapy | 0 (0-0) | 168.9 (484.7) | |
| Responders (n = 16) | |||
| Transfusion volume before combination therapy | 1575 (555-2362) | 1677.5 (1394.2) | .003 |
| Transfusion volume after combination therapy | 350 (0-975) | 618.7 (748.9) | |
| Nonresponders (n = 30) | |||
| Transfusion volume before combination therapy | 1050 (0-2100) | 1142.3 (1158.1) | .002 |
| Transfusion volume after combination therapy | 0 (0-1400) | 589 (748.5) | |
∼35 of 135 (ie, 25.9% of the patients) were already off transfusion of hydroxyurea only. ∼97 of 135 (ie, 71.9% of the patients) were off transfusion after 6 mo of combination therapy.
IQR, interquartile range.