Median change in laboratory values with respect to time (n = 135)
| . | Baseline . | 3 mo . | 6 mo . | Median change in 3 mo (IQR) . | Median change in 6 mo (IQR) . | P∗ . | P† . | P‡ . | P§ . |
|---|---|---|---|---|---|---|---|---|---|
| Hb, g/dL | 6.5 (5.8-7.3) | 8 (7.1-9.3) | 8.7 (7.5-9.8) | 1.6 (0.6-2.8) | 2.3 (1-3.4) | <.001 | <.001 | <.001 | <.001 |
| TLC | 8.3 (6-11.7) | 7.8 (6-10.6) | 7.9 (5.8-11) | 1.4 (0.6-3.4) | 1.8 (0.7-3.6) | .328 | .097 | .243 | .548 |
| Neutrophils | 3.2 (2.4-4.4) | 3 (2.1-4) | 2.5 (2-3.8) | 0.5 (0.3-1.2) | 0.9 (0.5-1.7) | <.001 | .005 | <.001 | .009 |
| Platelets | 270 (186-405) | 309 (237-429) | 309 (237-429) | 62 (29-136) | 89 (35-191.5) | .015 | .002 | .045 | .377 |
| Urea | 20 (16-26) | — | 20 (16-26) | — | 5 (2-10) | — | — | .764 | — |
| Creatinine | 0.4 (0.3-0.6) | — | 0.3 (0.3-0.5) | — | 0.1 (0.1-0.3) | — | — | .206 | — |
| Total bilirubin | 1.7 (1.1-2.5) | — | 1.6 (1.1-2) | — | 0.7 (0.3-1.2) | — | — | .122 | — |
| Direct bilirubin | 0.5 (0.4-1) | — | 0.5 (0.4-0.8) | — | 0.5 (0.3-1) | — | — | .895 | — |
| Indirect bilirubin | 0.9 (0.4-1.4) | 1.1 (0.6-1.4) | 0.4 (0.1-0.7) | — | — | .207 | — | ||
| SGPT | 35 (24-52) | — | 40 (24-55) | — | 14 (5-26) | — | — | 156 | — |
| Ferritin | 912 (399.9-1660) | 871 (400-1500) | — | 208 (41-460) | — | — | <.001 | — | |
| Liver size, cm | 10 (9.3-12.2) | — | 9.5 (9.1-12) | — | 0.5 (0.1-1.1) | — | — | .041 | — |
| Spleen size, cm (n = 89) | 9.8 (8.1-12.5) | — | 9.6 (8-12) | — | 0.7 (0.2-1.6) | — | — | <.001 | — |
| . | Baseline . | 3 mo . | 6 mo . | Median change in 3 mo (IQR) . | Median change in 6 mo (IQR) . | P∗ . | P† . | P‡ . | P§ . |
|---|---|---|---|---|---|---|---|---|---|
| Hb, g/dL | 6.5 (5.8-7.3) | 8 (7.1-9.3) | 8.7 (7.5-9.8) | 1.6 (0.6-2.8) | 2.3 (1-3.4) | <.001 | <.001 | <.001 | <.001 |
| TLC | 8.3 (6-11.7) | 7.8 (6-10.6) | 7.9 (5.8-11) | 1.4 (0.6-3.4) | 1.8 (0.7-3.6) | .328 | .097 | .243 | .548 |
| Neutrophils | 3.2 (2.4-4.4) | 3 (2.1-4) | 2.5 (2-3.8) | 0.5 (0.3-1.2) | 0.9 (0.5-1.7) | <.001 | .005 | <.001 | .009 |
| Platelets | 270 (186-405) | 309 (237-429) | 309 (237-429) | 62 (29-136) | 89 (35-191.5) | .015 | .002 | .045 | .377 |
| Urea | 20 (16-26) | — | 20 (16-26) | — | 5 (2-10) | — | — | .764 | — |
| Creatinine | 0.4 (0.3-0.6) | — | 0.3 (0.3-0.5) | — | 0.1 (0.1-0.3) | — | — | .206 | — |
| Total bilirubin | 1.7 (1.1-2.5) | — | 1.6 (1.1-2) | — | 0.7 (0.3-1.2) | — | — | .122 | — |
| Direct bilirubin | 0.5 (0.4-1) | — | 0.5 (0.4-0.8) | — | 0.5 (0.3-1) | — | — | .895 | — |
| Indirect bilirubin | 0.9 (0.4-1.4) | 1.1 (0.6-1.4) | 0.4 (0.1-0.7) | — | — | .207 | — | ||
| SGPT | 35 (24-52) | — | 40 (24-55) | — | 14 (5-26) | — | — | 156 | — |
| Ferritin | 912 (399.9-1660) | 871 (400-1500) | — | 208 (41-460) | — | — | <.001 | — | |
| Liver size, cm | 10 (9.3-12.2) | — | 9.5 (9.1-12) | — | 0.5 (0.1-1.1) | — | — | .041 | — |
| Spleen size, cm (n = 89) | 9.8 (8.1-12.5) | — | 9.6 (8-12) | — | 0.7 (0.2-1.6) | — | — | <.001 | — |