Table 1.

Baseline characteristics with respect to the outcome of the patients

Overall Median (IQR)Good responder (n = 89) Median (IQR)Responder (n = 16) Median (IQR)Nonresponder (n = 30) Median (IQR)P
Age, y 6 (3-10) 5 (3-8.5) 6.5 (3.2-10.7) 7 (3-12.2) .101  
Weight, kg 17 (12-24) 16 (11.2-22) 20 (16.2-26.5) 20 (12-33) .075  
Age at first transfusion, mo 9 (6-15) 9 (6-14) 7.5 (3.2-1.6) 9 (5.7-1.4) .824  
Age at the start of HU, y 1.2 (0.9-2.5) 1 (0.9-2) 2.1 (1-4.8) 1.6 (0.8-4) .252  
HbA electrophoresis, n = 12 5.7 (2.4-11.2) 3.2 (2.1-10.8) 6.6 (6.6-6.6) 7.8 (5.1-7.8) .392  
HbA2 electrophoresis, n = 45 2.6 (2-4.1) 2.8 (2.2-4) 2.3 (1.3-4.1) 2.2 (1.6-4.2) .606  
HbF electrophoresis, n = 76 96.4 (94-98) 96.6 (94.1-97.9) 96.2 (60.8-97.7) 96.3 (92.7-97.8) .851  
Overall Median (IQR)Good responder (n = 89) Median (IQR)Responder (n = 16) Median (IQR)Nonresponder (n = 30) Median (IQR)P
Age, y 6 (3-10) 5 (3-8.5) 6.5 (3.2-10.7) 7 (3-12.2) .101  
Weight, kg 17 (12-24) 16 (11.2-22) 20 (16.2-26.5) 20 (12-33) .075  
Age at first transfusion, mo 9 (6-15) 9 (6-14) 7.5 (3.2-1.6) 9 (5.7-1.4) .824  
Age at the start of HU, y 1.2 (0.9-2.5) 1 (0.9-2) 2.1 (1-4.8) 1.6 (0.8-4) .252  
HbA electrophoresis, n = 12 5.7 (2.4-11.2) 3.2 (2.1-10.8) 6.6 (6.6-6.6) 7.8 (5.1-7.8) .392  
HbA2 electrophoresis, n = 45 2.6 (2-4.1) 2.8 (2.2-4) 2.3 (1.3-4.1) 2.2 (1.6-4.2) .606  
HbF electrophoresis, n = 76 96.4 (94-98) 96.6 (94.1-97.9) 96.2 (60.8-97.7) 96.3 (92.7-97.8) .851  
n (%)n (%)n (%)n (%)
Sex 
Male 77 (57) 42 (47.2) 6 (37.5) 10 (33.3) .372  
Female 58 (43) 47 (52.8) 10 (62.5) 20 (66.7)  
n (%)n (%)n (%)n (%)
Sex 
Male 77 (57) 42 (47.2) 6 (37.5) 10 (33.3) .372  
Female 58 (43) 47 (52.8) 10 (62.5) 20 (66.7)  

P ≤ .05 considered significant.

IQR, interquartile range.

Kruskal-Wallis test applied.

χ2 test applied.

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