Table 3.

Four-year PFS and OS according to prognostic scoring systems in the PETAL, GOYA, and RW series

ScoresPETALGOYARW
4-y PFS, % (95% CI)4-y OS, % (95% CI)4-y PFS, % (95% CI)4-y OS, % (95% CI)4-y PFS, % (95% CI)4-y OS, % (95% CI)
TMTV/ECOG-PS high risk  54 (39-67) 61 (45-73) 49 (40-59) 61 (52-70) 36 (24-48) 41 (28-53) 
IPI 3-5 59 (52-66) 70 (63-76) 58 (54-62) 72 (69-76) 55 (48-62) 59 (52-65) 
TMTV/ECOG-PS intermediate risk  57 (50-64) 72 (65-79) 65 (61-69) 80 (76-83) 57 (47-65) 64 (54-72) 
IPI 0-2 79 (73-83) 86 (82-90) 73 (70-76) 85 (83-88) 75 (67-81) 84 (77-89) 
TMTV/ECOG-PS low risk 84 (79-88) 90 (85-93) 73 (69-77) 85 (82-89) 78 (71-83) 84 (77-89) 
ScoresPETALGOYARW
4-y PFS, % (95% CI)4-y OS, % (95% CI)4-y PFS, % (95% CI)4-y OS, % (95% CI)4-y PFS, % (95% CI)4-y OS, % (95% CI)
TMTV/ECOG-PS high risk  54 (39-67) 61 (45-73) 49 (40-59) 61 (52-70) 36 (24-48) 41 (28-53) 
IPI 3-5 59 (52-66) 70 (63-76) 58 (54-62) 72 (69-76) 55 (48-62) 59 (52-65) 
TMTV/ECOG-PS intermediate risk  57 (50-64) 72 (65-79) 65 (61-69) 80 (76-83) 57 (47-65) 64 (54-72) 
IPI 0-2 79 (73-83) 86 (82-90) 73 (70-76) 85 (83-88) 75 (67-81) 84 (77-89) 
TMTV/ECOG-PS low risk 84 (79-88) 90 (85-93) 73 (69-77) 85 (82-89) 78 (71-83) 84 (77-89) 

Two risk factors, ECOG-PS ≥2 and TMTV >220 cm3.

One risk factor, ECOG-PS ≥2 and TMTV ≤220 cm3 or ECOG-PS <2 and TMTV >220 cm3.

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