Incidence of primary outcome events in patients with negative D-dimer (who stopped anticoagulation)
| Characteristic . | Patients with event vs all patients with the characteristic . | Incidence per 100 person-years, % (95% CI) . | P value . |
|---|---|---|---|
| Overall | 21/286 | 6.2 (3.9-9.5) | — |
| Nature of index event | |||
| Unprovoked | 18/185 | 8.4 (5.0-13.3) | .0321 |
| Weak risk factors | 3/101 | 2.5 (0.5-7.2) | — |
| Age, y | |||
| <51 | 6/138 | 3.6 (1.3-7.9) | .0460 |
| 51-74 | 15/148 | 8.9 (5.0-14.7) | — |
| Type of index event | |||
| DVT with/without PE | 14/206 | 5.8 (3.2-9.7) | .5661 |
| Isolated PE | 7/79 | 7.5 (3.0-15.5) | — |
| 1 missing | |||
| Sex | |||
| Male | 14/148 | 8.1 (4.4-13.6) | .1520 |
| Female | 7/138 | 4.3 (1.7-8.9) | — |
| Women | |||
| With unprovoked events | 5/62 | 6.7 (2.2-15.8) | .3131 |
| With events associated with HT | 2/56 | 3.0 (0.4-10.8) | — |
| Duration of anticoagulation before inclusion, mo | |||
| 12-18 | 16/230 | 5.9 (3.4-9.6) | .5732 |
| >18 | 5/56 | 7.8 (2.5-18.2) | — |
| BMI | |||
| ≤24.9 | 8/118 | 5.9 (2.6-11.7) | .9155 |
| 25-30 | 9/105 | 7.0 (3.2-13.3) | — |
| >30 | 4/69 | 5.8 (1.6-14.8) | — |
| 4 missing | |||
| Characteristic . | Patients with event vs all patients with the characteristic . | Incidence per 100 person-years, % (95% CI) . | P value . |
|---|---|---|---|
| Overall | 21/286 | 6.2 (3.9-9.5) | — |
| Nature of index event | |||
| Unprovoked | 18/185 | 8.4 (5.0-13.3) | .0321 |
| Weak risk factors | 3/101 | 2.5 (0.5-7.2) | — |
| Age, y | |||
| <51 | 6/138 | 3.6 (1.3-7.9) | .0460 |
| 51-74 | 15/148 | 8.9 (5.0-14.7) | — |
| Type of index event | |||
| DVT with/without PE | 14/206 | 5.8 (3.2-9.7) | .5661 |
| Isolated PE | 7/79 | 7.5 (3.0-15.5) | — |
| 1 missing | |||
| Sex | |||
| Male | 14/148 | 8.1 (4.4-13.6) | .1520 |
| Female | 7/138 | 4.3 (1.7-8.9) | — |
| Women | |||
| With unprovoked events | 5/62 | 6.7 (2.2-15.8) | .3131 |
| With events associated with HT | 2/56 | 3.0 (0.4-10.8) | — |
| Duration of anticoagulation before inclusion, mo | |||
| 12-18 | 16/230 | 5.9 (3.4-9.6) | .5732 |
| >18 | 5/56 | 7.8 (2.5-18.2) | — |
| BMI | |||
| ≤24.9 | 8/118 | 5.9 (2.6-11.7) | .9155 |
| 25-30 | 9/105 | 7.0 (3.2-13.3) | — |
| >30 | 4/69 | 5.8 (1.6-14.8) | — |
| 4 missing | |||
BMI, body mass index; HT, hormonal therapy.