Baseline domain scores for the EORTC QLQ-C30 and FACT-LymS
| HRQOL measure, mean (SD) . | Liso-cel (n = 47) . | SOC (n = 43) . | Overall (N = 90) . | General population∗ . |
|---|---|---|---|---|
| EORTC QLQ-C30 | ||||
| Global health status/QOL | 67.7 (21.5) | 68.2 (22.1) | 68.0 (21.7) | 65.8 |
| Physical functioning | 83.3 (17.2) | 87.9 (14.9) | 85.5 (16.2) | 84.7 |
| Role functioning | 75.2 (25.7) | 74.4 (24.8) | 74.8 (25.1) | 84.1 |
| Emotional functioning | 73.9 (20.2) | 74.5 (21.2) | 74.2 (20.6) | 75.8 |
| Cognitive functioning | 83.7 (20.1) | 92.2 (12.2) | 87.8 (17.3) | 85.6 |
| Social functioning | 72.3 (25.6) | 72.4 (22.9) | 72.2 (24.2) | 86.8 |
| Fatigue | 34.5 (24.8) | 26.9 (20.4) | 30.9 (22.9) | 28.1 |
| Nausea/vomiting | 7.8 (12.5) | 7.4 (19.7) | 7.6 (16.2) | 4.8 |
| Pain | 30.5 (30.0) | 25.6 (27.1) | 28.2 (28.6) | 24.0 |
| Dyspnea | 12.1 (18.9) | 12.4 (23.0) | 12.2 (20.9) | 16.2 |
| Insomnia | 25.5 (29.7) | 27.9 (28.1) | 26.7 (28.8) | 26.9 |
| Appetite loss | 20.6 (25.6) | 12.4 (24.2) | 16.7 (25.1) | 8.9 |
| Constipation | 9.2 (18.0) | 7.8 (17.6) | 8.5 (17.7) | 11.6 |
| Diarrhea | 9.2 (23.8) | 7.8 (20.4) | 8.5 (22.1) | 8.6 |
| Financial difficulties | 19.9 (29.2) | 14.0 (25.4) | 17.0 (27.5) | 10.2 |
| FACT-LymS | 46.2 (9.6) | 49.0 (5.9) | 47.5 (8.1) | — |
| HRQOL measure, mean (SD) . | Liso-cel (n = 47) . | SOC (n = 43) . | Overall (N = 90) . | General population∗ . |
|---|---|---|---|---|
| EORTC QLQ-C30 | ||||
| Global health status/QOL | 67.7 (21.5) | 68.2 (22.1) | 68.0 (21.7) | 65.8 |
| Physical functioning | 83.3 (17.2) | 87.9 (14.9) | 85.5 (16.2) | 84.7 |
| Role functioning | 75.2 (25.7) | 74.4 (24.8) | 74.8 (25.1) | 84.1 |
| Emotional functioning | 73.9 (20.2) | 74.5 (21.2) | 74.2 (20.6) | 75.8 |
| Cognitive functioning | 83.7 (20.1) | 92.2 (12.2) | 87.8 (17.3) | 85.6 |
| Social functioning | 72.3 (25.6) | 72.4 (22.9) | 72.2 (24.2) | 86.8 |
| Fatigue | 34.5 (24.8) | 26.9 (20.4) | 30.9 (22.9) | 28.1 |
| Nausea/vomiting | 7.8 (12.5) | 7.4 (19.7) | 7.6 (16.2) | 4.8 |
| Pain | 30.5 (30.0) | 25.6 (27.1) | 28.2 (28.6) | 24.0 |
| Dyspnea | 12.1 (18.9) | 12.4 (23.0) | 12.2 (20.9) | 16.2 |
| Insomnia | 25.5 (29.7) | 27.9 (28.1) | 26.7 (28.8) | 26.9 |
| Appetite loss | 20.6 (25.6) | 12.4 (24.2) | 16.7 (25.1) | 8.9 |
| Constipation | 9.2 (18.0) | 7.8 (17.6) | 8.5 (17.7) | 11.6 |
| Diarrhea | 9.2 (23.8) | 7.8 (20.4) | 8.5 (22.1) | 8.6 |
| Financial difficulties | 19.9 (29.2) | 14.0 (25.4) | 17.0 (27.5) | 10.2 |
| FACT-LymS | 46.2 (9.6) | 49.0 (5.9) | 47.5 (8.1) | — |
—, data not available.
The EORTC QLQ-C30 norm scores are from the European general population data based on 11 European Union countries (N = 11 343)25; both were reweighted by EORTC QLQ-C30 analysis set patients’ age distributions by gender. Higher scores for the 5 functional domains and FACT-LymS indicate better QOL; lower scores on the 3 symptom domains indicate better QOL.