Table 1.

Demographic, physical characteristics, and laboratory results of the cohort of men with sickle cell anemia enrolled in the priapism study (n = 73)

Characteristic Summary statistics
Age, y 24.0 (21.5-28.5) 
Marital status, married 7 (9.6) 
BMI, kg/m2 17.9 (16.6-18.8) 
Systolic blood pressure, mm Hg 110.0 (104.5-117.0) 
Diastolic blood pressure, mm Hg 63.0 (56.0-68.5) 
On hydroxyurea 11 (15.1) 
Total hemoglobin, g/dL 8.0 (6.9-9.6) 
Mean cell volume, fl 84.9 (80.4-92.7) 
Percent hemoglobin, F% 4.6 (2.8-8.8) 
Percent hemoglobin, S% 85.6 (80.6-88.0) 
White blood cell count, 109/L 13.3 (9.6-17.6) 
Absolute neutrophil count, 109/L 6.45 (4.55-86.0) 
Platelet count, 109/L 297.0 (222.5-363.5) 
Lactate dehydrogenase, U/L 540.0 (379.0-729.0) 
Total bilirubin, mg/dL 79.0 (46.5-125.5) 
Direct conjugated bilirubin, mg/dL 16.0 (11.5-24.0) 
Indirect unconjugated bilirubin, mg/dL 79.0 (46.5-125.5) 
Aspartate aminotransferase, IU 46.0 (34.5-59.0) 
Alanine aminotransferase, IU 17.0 (13.0-25.5) 
Alkaline phosphatase, IU 98.0 (75.5-128.0) 
Albumin, g/L 42.0 (40.0-45.0) 
Globulin, g/L 38.0 (34.0-43.0) 
Testosterone, ng/dL 8.1 (6.4-10.1) 
Follicles stimulating hormone, mlU/mL 5.6 (4.0-7.3) 
Luteinizing hormone, mlU/mL 7.2 (5.5-9.9) 
Creatinine, μmol/L 59.0 (52.5-85.0) 
Urea 2.8 (2.3-5.2) 
Proteinuria, positive 26 (35.6) 
eGFR, mL/min/1.73 m2 155.0 (128.0-166.7) 
Stroke, n (%) 3 (4.1) 
Leg ulcer, n (%) 3 (4.1) 
Avascular necrosis 11 (15.1) 
Malaria, n (%) 55 (75) 
Blood transfusion, n (%) 25 (34.2) 
Characteristic Summary statistics
Age, y 24.0 (21.5-28.5) 
Marital status, married 7 (9.6) 
BMI, kg/m2 17.9 (16.6-18.8) 
Systolic blood pressure, mm Hg 110.0 (104.5-117.0) 
Diastolic blood pressure, mm Hg 63.0 (56.0-68.5) 
On hydroxyurea 11 (15.1) 
Total hemoglobin, g/dL 8.0 (6.9-9.6) 
Mean cell volume, fl 84.9 (80.4-92.7) 
Percent hemoglobin, F% 4.6 (2.8-8.8) 
Percent hemoglobin, S% 85.6 (80.6-88.0) 
White blood cell count, 109/L 13.3 (9.6-17.6) 
Absolute neutrophil count, 109/L 6.45 (4.55-86.0) 
Platelet count, 109/L 297.0 (222.5-363.5) 
Lactate dehydrogenase, U/L 540.0 (379.0-729.0) 
Total bilirubin, mg/dL 79.0 (46.5-125.5) 
Direct conjugated bilirubin, mg/dL 16.0 (11.5-24.0) 
Indirect unconjugated bilirubin, mg/dL 79.0 (46.5-125.5) 
Aspartate aminotransferase, IU 46.0 (34.5-59.0) 
Alanine aminotransferase, IU 17.0 (13.0-25.5) 
Alkaline phosphatase, IU 98.0 (75.5-128.0) 
Albumin, g/L 42.0 (40.0-45.0) 
Globulin, g/L 38.0 (34.0-43.0) 
Testosterone, ng/dL 8.1 (6.4-10.1) 
Follicles stimulating hormone, mlU/mL 5.6 (4.0-7.3) 
Luteinizing hormone, mlU/mL 7.2 (5.5-9.9) 
Creatinine, μmol/L 59.0 (52.5-85.0) 
Urea 2.8 (2.3-5.2) 
Proteinuria, positive 26 (35.6) 
eGFR, mL/min/1.73 m2 155.0 (128.0-166.7) 
Stroke, n (%) 3 (4.1) 
Leg ulcer, n (%) 3 (4.1) 
Avascular necrosis 11 (15.1) 
Malaria, n (%) 55 (75) 
Blood transfusion, n (%) 25 (34.2) 

Median (inter-quartile range) for continuous variables and counts (percentages) for categorical variables. BMI, body mass index; eGFR, estimated glomerular filtration rate (derived using CKD-EPI Creatinine Equation 2021).

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