Salient features of the pregnant patients treated with DA-REPOCH during the antepartum period
| Case . | Age at Dx (y) . | Initial presentation . | Initial WBC (k/μL) . | Initial Hgb (g/dL) . | Initial PLT (k/μL) . | LDH (U/L) ULN >190 . | R-IPI . | Staging studies . | Highest dose escalation . | Weeks pregnant at Dx . | Gestational weeks at the start of therapy . | Weeks at delivery . | Weight of baby at delivery (lbs) . | APGAR Score at delivery (out of 10) . | NICU . | Response to treatment . | Months in remission at last follow-up . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case 1 | 33 | SOB; chest pain | 13.43 | 11.7 | 261 | 752 | 1 | MRI A/P, CT chest, BMBx | 2 | 20 | 20w 5d | 37w 5d | 5.71 | 8 | No | CR | 35.2 |
| Case 2 | 36 | Left thigh pain and swelling | 14.5 | 9.6 | 496 | 958 | 3 | CT chest, MRI A/P, BMBx | 3 | 17 | 18 | 37w 5d | 7.56 | 8 | No | CR | 63.3 |
| Case 3 | 26 | SOB; facial swelling | 8.46 | 10.1 | 431 | 648 | Unable to calculate | CT chest | 3 | 30 | 31 | 36w 3d | 5.16 | 8 | No | CR | 17.9 |
| Case 4 | 39 | SOB; dyspnea on exertion | 7.63 | 11.1 | 267 | 233 | Unable to calculate | CT chest, MRI A/P | 3 | 15 | 16 | 35w 3d | 5.29 | 8 | Yes | CR | 7.4 |
| Case . | Age at Dx (y) . | Initial presentation . | Initial WBC (k/μL) . | Initial Hgb (g/dL) . | Initial PLT (k/μL) . | LDH (U/L) ULN >190 . | R-IPI . | Staging studies . | Highest dose escalation . | Weeks pregnant at Dx . | Gestational weeks at the start of therapy . | Weeks at delivery . | Weight of baby at delivery (lbs) . | APGAR Score at delivery (out of 10) . | NICU . | Response to treatment . | Months in remission at last follow-up . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case 1 | 33 | SOB; chest pain | 13.43 | 11.7 | 261 | 752 | 1 | MRI A/P, CT chest, BMBx | 2 | 20 | 20w 5d | 37w 5d | 5.71 | 8 | No | CR | 35.2 |
| Case 2 | 36 | Left thigh pain and swelling | 14.5 | 9.6 | 496 | 958 | 3 | CT chest, MRI A/P, BMBx | 3 | 17 | 18 | 37w 5d | 7.56 | 8 | No | CR | 63.3 |
| Case 3 | 26 | SOB; facial swelling | 8.46 | 10.1 | 431 | 648 | Unable to calculate | CT chest | 3 | 30 | 31 | 36w 3d | 5.16 | 8 | No | CR | 17.9 |
| Case 4 | 39 | SOB; dyspnea on exertion | 7.63 | 11.1 | 267 | 233 | Unable to calculate | CT chest, MRI A/P | 3 | 15 | 16 | 35w 3d | 5.29 | 8 | Yes | CR | 7.4 |
A/P, abdomen and pelvis; APGAR, appearance, pulse, grimace, activity, respiration; BMBx, bone marrow biopsy; CR, complete response; hgb, hemoglobin; LDH, lactate dehydrogenase; NICU, neonatal intensive care unit; plt, platelet; R-IPI, revised international prognostic index; SOB, shortness of breath; WBC, white blood cell.