Case reports of treatment of HL in patients with SCD
| Author . | Country . | SCD genotype . | HL stage, subtype . | Chemotherapy regimen . | Radiation . | Complications . |
|---|---|---|---|---|---|---|
| Paydas, 2002 | U.S. | Hgb SS | Stage II nodular sclerosing | ABVD | Mediastinal∗ | Asymptomatic hemolytic anemia |
| Ashraf, Kancharla, Goldfinger, 2019 | U.S. | —∗ | Stage II mixed cellularity | ABVD | 30 Gy IFRT + 6 Gy boost | N/A |
| Brown & Kotila, 2007 | Nigeria | Hgb SS | Stage IVB, mixed cellularity | COPP | N/A | Fever (cycle 3), S. aureus bacteremia (cycle 4), 3 VOE |
| Moschovi et al, 2001 | Greece | Hgb Sβ0 | Stage II, lymphocyte predominant | ABVD | N/A | Increased VOE with HU discontinuation, iron overload. BMT 4 years later for SCD |
| Couronné et al, 2008 | France | Hgb Sβ0 | Stage IIA∗ | MHD 03 (VBVP) | 20 Gy IFRT | N/A |
| Author . | Country . | SCD genotype . | HL stage, subtype . | Chemotherapy regimen . | Radiation . | Complications . |
|---|---|---|---|---|---|---|
| Paydas, 2002 | U.S. | Hgb SS | Stage II nodular sclerosing | ABVD | Mediastinal∗ | Asymptomatic hemolytic anemia |
| Ashraf, Kancharla, Goldfinger, 2019 | U.S. | —∗ | Stage II mixed cellularity | ABVD | 30 Gy IFRT + 6 Gy boost | N/A |
| Brown & Kotila, 2007 | Nigeria | Hgb SS | Stage IVB, mixed cellularity | COPP | N/A | Fever (cycle 3), S. aureus bacteremia (cycle 4), 3 VOE |
| Moschovi et al, 2001 | Greece | Hgb Sβ0 | Stage II, lymphocyte predominant | ABVD | N/A | Increased VOE with HU discontinuation, iron overload. BMT 4 years later for SCD |
| Couronné et al, 2008 | France | Hgb Sβ0 | Stage IIA∗ | MHD 03 (VBVP) | 20 Gy IFRT | N/A |
BMT, bone marrow transplant; COPP, cyclophosphamide, vincristine, procarbazine, prednisolone; Gy, gray; Hgb SS, hemoglobin SS; Hgb Sβ0, hemoglobin Sβ0; Hgb, hemoglobin; MHD 03 (VBVP), French national guidelines (vinblastine, bleomycin, etoposide, prednisone); N/A, not available.
Genotype, subtype, or dose not provided.