Summary of best overall response and response rates
| Parameter/variable rate . | GIL + AZA (n = 74) . | AZA (n = 49) . | Treatment difference (95% CI); P . |
|---|---|---|---|
| Response and composite response rate comparisons | |||
| CR | 12 (16.2) | 7 (14.3) | 2.0 (–12.5 to 16.5); .762 |
| CRh | 7 (9.5) | 1 (2.0) | 7.5 (–1.9 to 17.0); .100 |
| CR/CRh | 19 (25.7) | 8 (16.3) | 9.5 (–6.4 to 25.4); .212 |
| CRc∗ | 43 (58.1) | 13 (26.5) | 31.4 (13.1 to 49.7); <.001 |
| Response (CRc + PR) | 47 (63.5) | 17 (34.7) | 28.7 (9.7 to 47.6); .002 |
| Best overall response rate | |||
| CR | 12 (16.2) | 7 (14.3) | NA |
| CRp | 6 (8.1) | 0 | NA |
| CRi | 25 (33.8) | 6 (12.2) | NA |
| PR | 4 (5.4) | 4 (8.2) | NA |
| Not evaluable | 2 (2.7) | 1 (2.0) | NA |
| No response | 10 (13.5) | 17 (34.7) | NA |
| Parameter/variable rate . | GIL + AZA (n = 74) . | AZA (n = 49) . | Treatment difference (95% CI); P . |
|---|---|---|---|
| Response and composite response rate comparisons | |||
| CR | 12 (16.2) | 7 (14.3) | 2.0 (–12.5 to 16.5); .762 |
| CRh | 7 (9.5) | 1 (2.0) | 7.5 (–1.9 to 17.0); .100 |
| CR/CRh | 19 (25.7) | 8 (16.3) | 9.5 (–6.4 to 25.4); .212 |
| CRc∗ | 43 (58.1) | 13 (26.5) | 31.4 (13.1 to 49.7); <.001 |
| Response (CRc + PR) | 47 (63.5) | 17 (34.7) | 28.7 (9.7 to 47.6); .002 |
| Best overall response rate | |||
| CR | 12 (16.2) | 7 (14.3) | NA |
| CRp | 6 (8.1) | 0 | NA |
| CRi | 25 (33.8) | 6 (12.2) | NA |
| PR | 4 (5.4) | 4 (8.2) | NA |
| Not evaluable | 2 (2.7) | 1 (2.0) | NA |
| No response | 10 (13.5) | 17 (34.7) | NA |
Data are expressed as n (%).
CRh, complete remission with partial hematologic recovery; CRp, complete remission with incomplete platelet recovery; NA, not applicable; PR, partial response.
CRc is equal to CR + CRp + CRi.