Ten DEGs during basal VWF release with the greatest fold change
| Gene . | Protein . | Function . | Log2 fold change . | Adjusted P value . |
|---|---|---|---|---|
| SRGAP3 | SLIT-ROBO Rho GTPase-activating protein 3 | GTPase-activating protein for RAC1 and perhaps Cdc42 | −6.86 | 4.59E-03 |
| CD38 | CD38 | Type II membrane glycoprotein that plays a role in cell adhesion, migration, and signal transduction | −6.19 | 3.76E-02 |
| EMILIN1 | Elastin microfibril interfacer 1 | Extracellular matrix structural constituent; may be involved in the regulation of vessel assembly | −5.68 | 3.02E-02 |
| IGFBP2 | Insulin Like growth factor binding protein 2 | Inhibits IGF-mediated growth and developmental rates | −5.62 | 2.37E-02 |
| RBP1 | Retinol binding protein 1 | Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage, and retinoid homeostasis | −5.61 | 8.14E-02 |
| FAM110B | Family with sequence similarity 110 member B | May be involved in tumor progression | −5.49 | 2.57E-02 |
| LYPD6 | LYPD6 | Acts as a modulator of nicotinic acetylcholine receptors | −5.23 | 2.63E-02 |
| PCDH10 | PCDH10 | Potential calcium-dependent cell-adhesion protein | 5.10 | 1.41E-02 |
| LOC102723913 | Unknown | Unknown | −5.03 | 8.41E-02 |
| PRKCZ | Protein kinase C zeta | Involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, and inflammatory response | −4.94 | 1.88E-02 |
| Gene . | Protein . | Function . | Log2 fold change . | Adjusted P value . |
|---|---|---|---|---|
| SRGAP3 | SLIT-ROBO Rho GTPase-activating protein 3 | GTPase-activating protein for RAC1 and perhaps Cdc42 | −6.86 | 4.59E-03 |
| CD38 | CD38 | Type II membrane glycoprotein that plays a role in cell adhesion, migration, and signal transduction | −6.19 | 3.76E-02 |
| EMILIN1 | Elastin microfibril interfacer 1 | Extracellular matrix structural constituent; may be involved in the regulation of vessel assembly | −5.68 | 3.02E-02 |
| IGFBP2 | Insulin Like growth factor binding protein 2 | Inhibits IGF-mediated growth and developmental rates | −5.62 | 2.37E-02 |
| RBP1 | Retinol binding protein 1 | Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage, and retinoid homeostasis | −5.61 | 8.14E-02 |
| FAM110B | Family with sequence similarity 110 member B | May be involved in tumor progression | −5.49 | 2.57E-02 |
| LYPD6 | LYPD6 | Acts as a modulator of nicotinic acetylcholine receptors | −5.23 | 2.63E-02 |
| PCDH10 | PCDH10 | Potential calcium-dependent cell-adhesion protein | 5.10 | 1.41E-02 |
| LOC102723913 | Unknown | Unknown | −5.03 | 8.41E-02 |
| PRKCZ | Protein kinase C zeta | Involved in NF-kappa-B activation, mitogenic signaling, cell proliferation, cell polarity, and inflammatory response | −4.94 | 1.88E-02 |